Results 41 to 50 of about 164,527 (299)

Allele-specific DNA demethylation editing leads to stable upregulation of allele-specific gene expression

open access: yesiScience
Summary: Epigenome editing is an emerging technology that allows to rewrite epigenome states and reprogram gene expression. Here, we have developed allele-specific DNA demethylation editing at gene promoters containing an SNP by sgRNA/dCas9 mediated ...
Nivethika Rajaram   +3 more
doaj   +1 more source

Effective multi-functional biotechnological applications of protease/keratinase enzyme produced by new Egyptian isolate (Laceyella sacchari YNDH)

open access: yesJournal of Genetic Engineering and Biotechnology, 2020
Background Due to a multitude of industrial applications of keratinolytic proteases, their demands are increasing. The present investigation studied the production and monitoring of the most possible multi-functional applications of YNDH thermoalkaline ...
Doaa A. Goda   +4 more
doaj   +1 more source

Applied Mathematical Modelling in Evolutionary Biochemistry

open access: yes, 2023
This paper explores the use of applied mathematical modelling in the field of evolutionary biochemistry. The authors demonstrate how mathematical models can be applied to better understand the complex processes of evolution and biochemistry, and provide ...
Proshanta Sarkar (676289)   +1 more
core   +1 more source

Feather protein lysate optimization and feather meal formation using YNDH protease with keratinolytic activity afterward enzyme partial purification and characterization

open access: yesScientific Reports, 2021
Incubation parameters used for the creation of a protein lysate from enzymatically degraded waste feathers using crude keratinase produced by the Laceyella sacchari strain YNDH were optimized using the Response Surface Methodology (RSM); amino acids ...
Doaa A. Goda   +4 more
doaj   +1 more source

Imaging biochemistry: applications to breast cancer [PDF]

open access: yesBreast Cancer Research, 2000
The use of magnetic resonance spectroscopy (MRS) to investigate breast tumour biochemistry in vivo is reviewed. To this end, results obtained both from patients in vivo and from tumour extracts and model systems are discussed. An association has been observed between transformation and an increase in phosphomonoesters (PMEs) detected in the 31P MRS ...
Ronen, Sabrina M, Leach, Martin O
openaire   +4 more sources

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho   +7 more
wiley   +1 more source

Surveying Biochemistry Applications For Mobile Devices To Compare Availability And Topics Covered

open access: yes, 2016
We have surveyed the main mobile application stores to identify the coverage of the biochemistry applications and what kinds of applications are available in such stores.
Silva, Eduardo, Thanuci; Galembeck
core   +2 more sources

Differential increase in endocannabinoid levels at the plasma and intracellular membranes

open access: yesiScience
Summary: Endocannabinoids (eCBs) modulate the activity of proteins expressed at the plasma and intracellular membranes. Nothing is known about the dynamic changes in eCB levels in these subcellular compartments.
Simar Singh   +8 more
doaj   +1 more source

New Methods for Synthesizing DNA, RNA, and Phosphonates

open access: yesCHIMIA, 2005
The development of new methods for the synthesis of DNA, RNA, and phosphonates has enabled new applications in biochemistry and biology.
Marvin H. Caruthers
doaj   +1 more source

Photochemical spin-state control of binding configuration for tailoring organic color center emission in carbon nanotubes

open access: yesNature Communications, 2022
Chemical functionalization of the sidewalls of single-wall carbon nanotubes (SWCNTs) is an emerging route to introduce fluorescent quantum defects and tailor the emission properties.
Yu Zheng   +10 more
doaj   +1 more source

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