Results 81 to 90 of about 85,620 (210)

Epigenetic and antitumor effects of platinum(IV)-octanoato conjugates [PDF]

open access: yes, 2017
We present the anticancer properties of cis, cis, trans-[Pt(IV)(NH3)2Cl2(OA)2] [Pt(IV)diOA] (OA = octanoato), Pt(IV) derivative of cisplatin containing two OA units appended to the axial positions of a six-coordinate Pt(IV) center.
Brabec, Viktor   +8 more
core   +1 more source

Power source, data retrieval method, and attachment type affect success of dorsally mounted tracking tag deployments in 37 species of shorebirds

open access: yesJournal of Avian Biology, Volume 2025, Issue 6, November 2025.
Animal‐borne trackers are commonly used to study bird movements, including in long‐distance migrants such as shorebirds. Selecting a tracker and attachment method can be daunting, and methodological advancements often have been made by trial and error and conveyed by word of mouth.
Emily L. Weiser   +100 more
wiley   +1 more source

Allopurinol Treatment Improves Cognitive Skills, Adaptive Behavior, and Biochemical Markers in Young Patients With Adenylosuccinate Lyase Deficiency

open access: yesJournal of Inherited Metabolic Disease, Volume 48, Issue 6, November 2025.
ABSTRACT Adenylosuccinate lyase deficiency (ADSLD) is a rare neurological disorder characterized by psychomotor retardation, autistic behaviors, and seizures, with no specific treatment available. ADSL catalyzes the transformation of succinylaminoimidazole carboxamide ribotide (SAICAr) to AICAR, and succinyl‐AMP (S‐AMP) to AMP.
Bérangère Rousselot‐Pailley   +12 more
wiley   +1 more source

SAHA/TRAIL combination induces detachment and anoikis of MDA-MB231 and MCF-7 breast cancer cells [PDF]

open access: yes, 2012
SAHA, an inhibitor of histone deacetylase activity, has been shown to sensitize tumor cells to apoptosis induced by TRAIL, a member of TNF-family. In this paper we investigated the effect of SAHA/TRAIL combination in two breast cancer cell lines, the ...
CARLISI, Daniela   +4 more
core   +1 more source

Epigenetic Clock Analysis of Sex Chromosome Aneuploidies

open access: yesAging Cell, Volume 24, Issue 11, November 2025.
Next‐generation epigenetic clocks indicate lower age acceleration and slower pace of aging in 47,XXY than 46,XX, 46,XY, and 47,XYY. A first‐generation clock (Skin & Blood) indicates higher age acceleration in 47,XXY and 47,XYY than 46,XY, while higher naïve CD8+ T in 47,XXY than both 46,XY and 46,XX suggests reduced immunosenescence.
Joshua Zhang   +7 more
wiley   +1 more source

Effects of phorbol 12-myristate 13-acetate on triglyceride and cholesteryl ester synthesis in cultured coronary smooth muscle cells and macrophages.

open access: yesJournal of Lipid Research, 1990
In cultured pig coronary smooth muscle cells phorbol 12-myristate 13-acetate (PMA) stimulated the conversion of [4-14C]cholesterol into cholesteryl esters and the incorporation of [2-3H]glycerol into triglycerides 6.4- and 4.5-fold, respectively.
M Moinat   +4 more
doaj   +1 more source

RNA-RNA interaction prediction based on multiple sequence alignments

open access: yes, 2010
Many computerized methods for RNA-RNA interaction structure prediction have been developed. Recently, $O(N^6)$ time and $O(N^4)$ space dynamic programming algorithms have become available that compute the partition function of RNA-RNA interaction ...
Li, Andrew X.   +3 more
core   +1 more source

Detergents and Chaotropes for Protein Solubilization before Two-Dimensional Electrophoresis [PDF]

open access: yes, 2006
Because of the outstanding separating capabilities of two-dimensional electrophoresis for complete proteins, it would be advantageous to be able to apply it to all types of proteins.
Chevallet, Mireille   +3 more
core   +4 more sources

Crystallization, data collection and data processing of maltose-binding protein (MalE) from the phytopathogen Xanthomonas axonopodis pv. citri [PDF]

open access: yes, 2009
Maltose-binding protein is the periplasmic component of the ABC transporter responsible for the uptake of maltose/maltodextrins. The Xanthomonas axonopodis pv.
Balan, A.   +4 more
core   +3 more sources

Detection of the low density lipoprotein (LDL) receptor on nitrocellulose paper with colloidal gold-LDL conjugates.

open access: yesJournal of Lipid Research, 1987
Gold-low density lipoprotein (LDL) conjugates were used to detect the LDL receptor on nitrocellulose paper. Solubilized rat liver membrane proteins were subjected to electrophoresis and electroblotted onto nitrocellulose paper.
P D Roach, M Zollinger, S P Noël
doaj   +1 more source

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