Results 161 to 170 of about 67,723 (299)

Patient‐Derived Fibroblasts as a Clinically Relevant Model of Kearns–Sayre Syndrome

Annals of Neurology, EarlyView.
Objective Kearns–Sayre syndrome (KSS) is characterized by single large‐scale mitochondrial DNA deletions and by severe early‐onset clinical manifestations with neurological involvement. Reliable disease models, as well as validated biomarkers or effective treatments, are lacking.
Laura Valls‐Roca, Adrià Vilaseca‐Capel, Judith Cantó‐Santos, Ester Tobías, Félix Andújar‐Sánchez, Laia Farré‐Tarrats, Frederic Tort, Carles Rentero, Carlos Enrich, Virginia López, Juan R. Tejedor, Anna Esteve‐Codina, Cristina Núñez de Arenas, Pedro J. Moreno‐Lozano, José C. Milisenda, Mar O'Callaghan, Teresa García‐Silva, Montserrat Morales‐Conejo, Mario F. Fraga, Rafael Artuch, Miguel Á. Martín, José M. Cuezva, Ana Matas, Glòria Garrabou, Mariona Guitart‐Mampel   +24 more
wiley   +1 more source

A Mechanism-Centered Text-Mining Landscape of Mitochondrial Bioenergetics and Signaling in Disease Research. [PDF]

Int J Mol Sci
Yonar H, Beşoluk FÇ, Parlak TM.
europepmc   +1 more source

Circulating Exosomes Drive Persistent Neuronal Dysfunction in Post‐Herpetic Neuralgia Patients

Annals of Neurology, EarlyView.
Proposed model of exosome‐mediated neuronal dysfunction in post‐herpetic neuralgia (PHN). (1) Circulating, non‐pathogenic exosomes maintain homeostatic processes in healthy skin, where sensory nerve fibers innervate the epidermis and dermis. (2) During acute zoster, reactivating varicella zoster virus (VZV) travels down neurites to the skin causing ...
Christy S. Niemeyer, Seth Frietze, Serena W.R. Lewis, Emily C. Artman, Christina Coughlan, Safa I. Vaseemuddin, Arianna Gentile Polese, Maria A. Nagel, Stephen K. Tyring, Fyona Okundia, Anthony J. Saviola, Gary C. Curhan, Sharon G. Curhan, Diego Restrepo, Andrew N. Bubak   +14 more
wiley   +1 more source

Mitochondrial Complex V Dysfunction in Neurodegeneration: Secondary Bystander or Primary Driver? [PDF]

Brain Sci
Harris KE, Lascaratos G, Chau KY.
europepmc   +1 more source

Computational modeling of substrate-dependent lung mitochondrial respiration and bioenergetics in rats with different susceptibility to hyperoxia-induced ARDS. [PDF]

Am J Physiol Cell Physiol
Taheri P, Dave DD, Clough AV, Dash RK, Audi SH.   +4 more
europepmc   +1 more source

Micronutrition as a Therapeutic Strategy for Mitochondrial Dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Fibromyalgia: A Narrative Review. [PDF]

Nutrients
Abanades S, Fernández I, Capdevila N, Cardona F.   +3 more
europepmc   +1 more source

The Influence of Temperature and Forage Availability on Growth and Habitat Selection of a Pelagic Piscivore

, 2006
Habitat characteristics influencing growth of fishes often affect habitat selection because behaviors leading to rapid growth are under selective pressure.
Thompson, Jessica Suzanne
core  

Photobiomodulation in Age-Related Macular Degeneration: A Mitochondrial Bioenergetic Framework and Translational Perspective. [PDF]

Life (Basel)
Desmettre T, Mordon S.
europepmc   +1 more source

Heat Stress in Quail: Impacts on Health and Productivity, and Mitigation Strategies

Animal Research and One Health, EarlyView.
Heat stress disrupts physiological homeostasis in quail, inducing oxidative stress, immune dysregulation, and metabolic imbalance, which impair growth, reproduction, product quality, and welfare. Integrating nutritional, environmental, and genetic–epigenetic strategies enhances thermotolerance, sustains productivity, and supports climate‐smart quail ...
T. A. Eletu, I. A. Anjola, L. O. Fasasi, D. P. Fadipe, A. T. Afuye, F. O. Fasanya, O. E. Oke   +6 more
wiley   +1 more source

Targeting GSS-mediated glutathione synthesis: 6-Met induces oxidative stress dependent apoptosis via triggering mitochondrial bioenergetics metabolism crisis and mTOR suppression in glioblastoma. [PDF]

Redox Biol
Lin J, Zhou H, Ma N, Chen Y, Chen Q, Han S, Yang H, Zhang X, Shangguan F.   +8 more
europepmc   +1 more source