Chronic Exposure to <i>Gelsemium</i> Preparations Alters Mitochondrial Bioenergetics, Neurite Outgrowth, and Akt/mTOR Signaling in Human Neuronal Cells. [PDF]
Lejri I +5 more
europepmc +1 more source
Abstract Objective The ketogenic diet (KD) is a high‐fat, low‐carbohydrate intervention widely used to treat drug‐resistant epilepsy, thought to reduce seizures through a combination of metabolic, neuronal, and microbiota‐dependent mechanisms. Additionally, recent studies suggest that the anticonvulsant effects of KD require the gut microbiota, with ...
Casey H. Meili +4 more
wiley +1 more source
Toxicological Profile of a <i>Quercus laurina</i> Bark Extract Through Oral Administration: Impact on Hepatocyte Mitochondrial Bioenergetics. [PDF]
Hurtado-Nuñez GE +11 more
europepmc +1 more source
The genetic architecture of epilepsy across molecular mechanisms and clinical heterogeneity
Abstract Epilepsy comprises a highly heterogeneous group of neurological disorders unified by a persistent predisposition to recurrent seizures, yet driven by remarkably diverse genetic, molecular, and network‐level mechanisms. Advances in genomic technologies have revealed that epilepsy arises from a multilayered genetic architecture encompassing rare
Mohammad Reza Seyedtaghia +4 more
wiley +1 more source
Whole-Exome Sequencing Explores Host Genetic Susceptibility of COVID-19 Severity in Unvaccinated Vietnamese Patients Infected with the Delta Variant: A Hypothesis-Generating Study. [PDF]
Nguyen HTT +7 more
europepmc +1 more source
Synthetic Biology and Food: Applications and Prospects
Synthetic biology would provide revolutionary technological solutions to produce new food and feed components, such as artificial starch, animo acids, microbial protein, lipids, sweeteners, vitamins.
Yi‐Heng P. Job Zhang
wiley +1 more source
Myelination sustains axonal bioenergetics by storing and consuming oxygen for aerobic metabolism. [PDF]
Panfoli I, Candiano G, Bruschi M.
europepmc +1 more source
Acupuncture at Feishu (BL13), Shenshu (BL23), Yingxiang (LI20), and Dazhui (GV14) alleviates allergic rhinitis by activating the AMPK/PGC‐1α/NRF1/TFAM signalling axis. This activation improves mitochondrial biogenesis and function, reduces mtROS‐mediated oxidative stress, restores ATP production and respiratory complex I/IV activity, suppresses IgE and
Fengying Zhang +3 more
wiley +1 more source
Multienzymatic hybrid bio-heterojunction for synergistic microenvironment reprogramming and selenoprotein-activated mitochondrial bioenergetics in diabetic osseointegration. [PDF]
Zhang M +5 more
europepmc +1 more source

