Results 231 to 240 of about 67,723 (299)

Stem cell–mediated neuroplasticity and psychological recovery in cancer survivors: Mechanisms, evidence, and translational challenges

Precision Medical Sciences, EarlyView.
Cancer therapies can trigger neuroinflammation and disrupted neuroplasticity, contributing to cognitive impairment and psychological distress in survivors. Stem cells (NSCs/MSCs) and their extracellular vesicles may restore neural niches via trophic support, immunomodulation, synaptic remodeling, and vascular repair, but require rigorous safety, dosing,
Xinyi Yang
wiley   +1 more source

Assessing Pain Linked to High Metabolic and Glycolytic Shift in Neurofibromatosis Type 1 (NF1) Patients by Using a Bioenergetic Biomarker: A Pilot Study. [PDF]

Cureus
Miller GP, Krager K, Eom D, Aykin-Burns N, Santos-Horta E.   +4 more
europepmc   +1 more source

COX5A promotes cell progression and cisplatin‐resistance by alleviating mitochondrial dysfunction in head and neck squamous cell carcinoma

Precision Medical Sciences, EarlyView.
COX5A promotes cell progression and cisplatin‐resistance and alleviates mitochondrial dysfunction. ISG15 shows a reversing role with COX5A. Targeting the COX5A‐mediated mitochondrial metabolic pathway may offer a novel therapeutic approach to enhance cisplatin sensitivity in HNSCC.
Nannan Guo, Zhangyu Yao, Bo Gui, Qingya Sun, Yihan Tang, Tingting Hu, Yanbin Zhao, Fangzhou Liu   +7 more
wiley   +1 more source

Mitochondria as programmable redox rheostats: Advancing from transplantation to bioengineered organelle therapeutics. [PDF]

Redox Biol
Awasthi V, Lalu E, Saaoud F, Das A, Sharma P, Adnane E, Gerhard G, Mokashi S, Wang H, Bouchareb R.   +9 more
europepmc   +1 more source

Piper nigrum Has an Antitumor Effect Through Regulation of the Phosphatidylinositol 3‐Kinase Signaling Pathway in a Murine Model of Acute Myeloid Leukemia

Phytotherapy Research, EarlyView.
Overview of the antileukemic effects of Piper nigrum extract in AML. P. nigrum reduced leukemic cell proliferation and glycolytic metabolism through modulation of the PI3K/AKT/mTOR pathway. In vivo, treatment reduced leukemic burden, improved hematological parameters, prolonged survival, and modulated antitumor immune responses.
Natalia Murillo, Paola Lasso, Claudia Urueña, Susana Fiorentino   +3 more
wiley   +1 more source

Photobiomodulation with 808 nm Laser Light Repairs Mitochondrial Integrity and Normalizes ROS, ATP, and Membrane Depolarization in Aβ-Exposed Primary Neurons in Alzheimer's Disease Model. [PDF]

Int J Mol Sci
Golovynska I, Li B, Chen Q, Golovynskyi S, Xu H, Stepanov YV, Stepanova LI, Lin F, Qu J, Ohulchanskyy TY.   +9 more
europepmc   +1 more source

Regulating Lipid Metabolism in Cancer: The Therapeutic Potential of Traditional Chinese Medicine

Phytotherapy Research, EarlyView.
By regulating the reprogramming of lipid metabolism in tumor cells, TCM provides a novel strategy for antitumor therapy with reduced toxicity and enhanced efficacy. ABSTRACT Lipid metabolic reprogramming is a key feature of tumor cells to adapt to the microenvironment and plays an important role in tumor growth, invasion, and metastasis.
Yufeng Gao, Huiming Huang, Xuejiao Wei, Xiaoxue Wang, Wanying Xie, Xinyu Qiu, Fei Wang, Zhuguo Wang, Ruoxin Zhang, Yilin Cai, Changhai Qu, Zhongdong Hu   +11 more
wiley   +1 more source

Platelet Mitochondrial Function, Physical Performance, and Body Composition in Older People Living with HIV: A Preliminary Study. [PDF]

Int J Mol Sci
Schuh RA, Jaber SM, Oursler KK, Ryan AS.
europepmc   +1 more source

Food Additive Titanium Dioxide (E171) Increases Intracellular Labile Fe²⁺ Levels and Induces Oxidative Stress and Mitochondrial Dysfunction in H9c2 Cardiomyoblasts. [PDF]

J Xenobiot
Cruz-Gregorio A, Silva-Palacios A, Belmont-Díaz JA, Ramos-Godinez MDP, López-Marure R.   +4 more
europepmc   +1 more source

Dissipation of the mitochondrial proton motive force drives sepsis pathogenesis and explains hyperlactatemia's predictive value in sepsis mortality. [PDF]

World J Crit Care Med
Pravda J.
europepmc   +1 more source