Results 41 to 50 of about 67,723 (299)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Hydrogenation of CO2 at ambient pressure catalyzed by a highly active thermostable biocatalyst

Biotechnology for Biofuels, 2018
Background Replacing fossil fuels as energy carrier requires alternatives that combine sustainable production, high volumetric energy density, easy and fast refueling for mobile applications, and preferably low risk of hazard. Molecular hydrogen (H2) has
Fabian M. Schwarz, Kai Schuchmann, Volker Müller   +2 more
doaj   +1 more source

A temperature dependent pilin promoter for production of thermostable enzymes in Thermus thermophilus

Microbial Cell Factories, 2023
Background Enzymes from thermophiles are of great interest for research and bioengineering due to their stability and efficiency. Thermophilic expression hosts such as Thermus thermophilus [T.
Lennart Kirchner, Volker Müller, Beate Averhoff   +2 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Physiological stress responses of Hydrilla verticillata to spent engine oil contamination leading to impairment of photosystem II photochemistry and oxidative destabilization

Discover Plants
The indiscriminate release of spent engine oil (SEO) into aquatic ecosystems poses a significant environmental threat due to its complex composition of petroleum hydrocarbons, heavy metals, and oxidative degradation products.
Komal Sharma, Dipti Agarwal, Upma Bhatt, Vineet Soni   +3 more
doaj   +1 more source

Integrated computational model of the bioenergetics of isolated lung mitochondria. [PDF]

PLoS ONE, 2018
Integrated computational modeling provides a mechanistic and quantitative framework for describing lung mitochondrial bioenergetics. Thus, the objective of this study was to develop and validate a thermodynamically-constrained integrated computational ...
Xiao Zhang, Ranjan K Dash, Elizabeth R Jacobs, Amadou K S Camara, Anne V Clough, Said H Audi   +5 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Air pollution drives photosynthetic breakdown and metabolic stress in Semibarbula orientalis

Discover Plants
Air quality plays a pivotal role in regulating plant productivity and ecological stability. However, rapid urbanization and escalating vehicular emissions have severely altered atmospheric composition, exposing plants to intense oxidative, metabolic, and
Vineet Soni, Upma Bhatt, Dipti Agarwal, Yashwant Sompura   +3 more
doaj   +1 more source

The Relationship between Mitochondrial Reactive Oxygen Species Production and Mitochondrial Energetics in Rat Tissues with Different Contents of Reduced Coenzyme Q

Antioxidants, 2021
We investigated the relationship between mitochondrial production of reactive oxygen species (ROS) and mitochondrial energetics in various rat tissues with different contents of the reduced coenzyme Q (Q) pool (Q9 + Q10).
Karolina Dominiak, Wieslawa Jarmuszkiewicz   +1 more
doaj   +1 more source