Results 61 to 70 of about 67,723 (299)

Integrated Computational Model of Lung Tissue Bioenergetics [PDF]

, 2019
Altered lung tissue bioenergetics plays a key role in the pathogenesis of lung diseases. A wealth of information exists regarding the bioenergetic processes in mitochondria isolated from rat lungs, cultured pulmonary endothelial cells, and intact rat ...
Dexuan Xie, Elizabeth R. Jacobs, Ranjan K. Dash, Anne V. Clough, Xiao Zhang, Said H. Audi   +5 more
core   +1 more source

Cell‐Based Biohybrid Micro/Nanorobots for Biotherapy

Advanced Robotics Research, EarlyView.
This review systematically evaluates cell‐based biohybrid micro/nanorobots (CB‐BMRs), highlighting their cell selection criteria, fabrication strategies, and diverse actuation modes. Furthermore, it surveys the promising therapeutic applications of CB‐BMRs in targeted cancer, thrombosis, and inflammation treatments, while comprehensively discussing ...
Lin Wang, Chenlu Liu, Yu Zhao, Chuanhua Li, Xuyang Chen, Shixiao Ding, Lizhou Dai, Guokun Wang, Tianlong Li, Jiaxin Li, Xuejia Liu, Haocheng Wang   +11 more
wiley   +1 more source

Effect of different waterlogging periods on biochemistry, growth, and chlorophyll a fluorescence of Arachis hypogaea L.

Frontiers in Plant Science, 2022
Peanut is among the main oil crops in India with huge economic importance. The unpredictable rainy season during the growing time of peanuts causes waterlogging in peanut fields.
Shubhangani Sharma, Upma Bhatt, Jyotshana Sharma, Ahmad Darkalt, Jacek Mojski, Jacek Mojski, Vineet Soni   +6 more
doaj   +1 more source

Phosphorylation‐Facilitated CKB Lactylation At K11 By GCN5 Enhances Creatine Kinase Activity and Mitigates Neuronal Damage After Cerebral Ischemia‐Reperfusion

Advanced Science, EarlyView.
This study uncovers hierarchical coordination between K11 lactylation and S199 phosphorylation of CKB in cerebral ischemia‐reperfusion injury. Such dual modifications potentiate CKB enzymatic function, remodel energy metabolism, alleviate oxidative stress and neuronal damage, and represent a viable therapeutic target for stroke treatment.
Chao Duan, Ruolin Zhang, Shihui Ding, Ying Feng, Tao Shen, Ziwei Wang, Wendai Bao, Ke Shui, Jun Qin, Jun Chen, Min Zhang, Zijing Ren, Dongmei Zhao, Xingrong Guo, Zhibing Ai, Xin Yang, Peiyang Zhou, Zhiqiang Dong   +17 more
wiley   +1 more source

Impact of synthetic and herbal dyes on photosynthesis and ROS scavenging enzyme activities in Spirodela polyrhiza

Scientific Reports
Synthetic colors (SCs) are widely used in various industries, yet their discharge into aquatic ecosystems poses a significant environmental threat. This study investigates the impact of SCs and herbal colors (HCs), used during the ‘festival of colors ...
Vineet Soni, Upma Bhatt, Pooja Tailor, Reto J. Strasser   +3 more
doaj   +1 more source

TRIM Proteins in Colorectal Cancer: TRIM8 as a Promising Therapeutic Target in Chemo Resistance

Biomedicines, 2021
Colorectal cancer (CRC) represents one of the most widespread forms of cancer in the population and, as all malignant tumors, often develops resistance to chemotherapies with consequent tumor growth and spreading leading to the patient’s premature death.
Flaviana Marzano, Mariano Francesco Caratozzolo, Graziano Pesole, Elisabetta Sbisà, Apollonia Tullo   +4 more
doaj   +1 more source

Compensatory Mitophagy via NEDD4/HIF‐1α/BNIP3 Pathway Restrains EndMT and Renal Allograft Interstitial Fibrosis Induced by TNFα

Advanced Science, EarlyView.
The role of TNFα in the process of renal allograft interstitial fibrosis is complex and multifaceted. As it can promote renal allograft interstitial fibrosis by inducing mitochondrial dysfunction and EndMT, and also mediating compensatory mitophagy through the NEDD4–HIF‐1α–BNIP3 pathway, which clears damaged mitochondria and inhibits EndMT, thereby ...
Dengyuan Feng, Qinghuan Shen, Junqi Zhang, Jiawen Liu, Zeping Gui, Zijie Wang, Qianguang Han, Shuang Fei, Hao Chen, Li Sun, Jun Tao, Zhijian Han, Xiaobing Ju, Min Gu, Jianjian Zhang, Ruoyun Tan   +15 more
wiley   +1 more source

Nutritional bioenergetics in fishes and shellfishes [PDF]

, 1987
Matter or energy can neither be created nor destroyed but can be converted thus says the second law of thermodynamics, which is the cardinal concept in bioenergetics.
Easterson, D C V
core   +1 more source

Disrupted TFEB/GDNF–cAMP/ATP Coupling Underlies Astrocytic Dysfunction and Depression in LRRK2 G2019S Parkinson's Mice

Advanced Science, EarlyView.
ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao, Maryam Hatami, Sumeyye Koc, Qing Jiang, Thomas Skutella, Yuanfeng Zhang   +5 more
wiley   +1 more source

Determination, measurement, and validation of maximal aerobic speed

Scientific Reports, 2023
This study determined Maximal Aerobic Speed (MAS) at a speed that utilizes maximal aerobic and minimal anaerobic contributions. This method of determining MAS was compared between endurance (ET) and sprint (ST) trained athletes.
Govindasamy Balasekaran, Mun Keong Loh, Peggy Boey, Yew Cheo Ng   +3 more
doaj   +1 more source