Therapeutic monoclonal antibodies: scFv patents as a marker of a new class of potential biopharmaceuticals [PDF]
Brazilian Journal of Pharmaceutical Sciences, 2011 Monoclonal antibodies represent the fastest growing class of biopharmaceutical products and have a host of applications in medical research, diagnosis, therapy, and basic science. The production of recombinant monoclonal antibodies has revolutionized the
Manuela Berto Pucca +4 more
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Multi-model approach to understand and predict past and future dengue epidemic dynamics [PDF]
Royal Society Open ScienceUnderstanding the past, current and future dynamics of dengue epidemics is challenging yet increasingly important for global public health. Using data from northern Peru across 2010–2021, we introduce a multi-model approach that integrates new and ...
Cathal Mills +5 more
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The Deleterious Effects of Shiga Toxin Type 2 Are Neutralized In Vitro by FabF8:Stx2 Recombinant Monoclonal Antibody [PDF]
Toxins, 2021 Hemolytic Uremic Syndrome (HUS) associated with Shiga-toxigenic Escherichia coli (STEC) infections is the principal cause of acute renal injury in pediatric age groups.
Daniela Luz +13 more
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Opposite effects of systemic and local conditional CD11c+ myeloid cell depletion during bleomycin-induced inflammation and fibrosis in mice. [PDF]
Immun Inflamm DisDendritic cells (DCs) and macrophages (MΦ) are key antigen‐presenting cells (APCs) that direct adaptive immunity. The role of CD11c+ myeloid cells in lung extracellular matrix (ECM) accumulation and pulmonary fibrosis is not well understood. Systemic depletion of CD11c+ cells confers protection against inflammation and fibrosis induced by bleomycin ...
Lopes GAO +9 more
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Produção in vitro de embriões de ovinos: uma visão crítica do método e de seu resultado a campo In vitro embryo production in ovine: critical vision of the method and of the field results [PDF]
Revista Brasileira de Zootecnia, 2009 A metodologia de produção in vitro de embriões de ovinos implica no desenvolvimento de meios de maturação, fertilização e cultivo que permitam aumentar a taxa de clivagem e desenvolvimento, tanto para o investimento biotecnológico em programas comerciais,
Anneliese de Souza Traldi
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Development of bivalent RBD adapted COVID-19 vaccines for broad sarbecovirus immunity [PDF]
npj VaccinesCOVID-19 vaccine adaptation is critical to respond to continuously emerging SARS-CoV-2 variants with enhanced immune evasion. The ARVAC protein subunit vaccine, based on the receptor binding domain of the spike protein of SARS-CoV-2, has been adapted to ...
Laura A. Bruno +19 more
doaj +2 more sources
Tratamientos y bioterapias para COVID-19
Revista del Hospital Italiano de Buenos Aires, 2022 Introducción: Un nuevo brote de coronavirus surgió en 2019 en Wuhan, China, causando conmoción en el sistema sanitario de todo el mundo; el Comité Internacional de Taxonomía de Virus lo denominó SARS-CoV-2, agente causante de la enfermedad COVID-19 ...
Aída E. Sterin Prync +4 more
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Forms and Methods for Interferon’s Encapsulation
Pharmaceutics, 2021 Interferons (IFNs) are cytokines involved in the immune response that act on innate and adaptive immunity. These proteins are natural cell-signaling glycoproteins expressed in response to viral infections, tumors, and biological inducers and constitute ...
Thelvia I. Ramos +6 more
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The Hitchhiker’s Guide to Human Therapeutic Nanoparticle Development
Pharmaceutics, 2022 Nanomedicine plays an essential role in developing new therapies through novel drug delivery systems, diagnostic and imaging systems, vaccine development, antibacterial tools, and high-throughput screening. One of the most promising drug delivery systems
Thelvia I. Ramos +6 more
doaj +1 more source
Journal of Technology Management & Innovation, 2017 Desde una perspectiva de sustitución de importaciones basada en la industria infantil, la protección del mercado interno es necesaria como un primer paso para generar un proceso de aprendizaje tecnológico.
Pablo José Lavarello +2 more
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