Results 41 to 50 of about 5,403 (178)

Salvia coccinea and Apigenin: A Natural Treasure of Lamiaceae in Pharmacological Innovation

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Salvia coccinea is rich in bioactive phytochemicals, notably the flavonoid apigenin, offering strong antioxidant, anti‐inflammatory, and antimicrobial effects. By modulating inflammatory and oxidative pathways, it shows potential for managing chronic diseases.
Muhammad Usman Khalid, Muhammad Tauseef Sultan, Muhammad Maaz, Shehnshah Zafar, Anum Shoukat, Nudrat Khursheed, Matteo Bordiga, Amna Junaid   +7 more
wiley   +1 more source

Emerging Medications for Treatment-Resistant Depression: A Review with Perspective on Mechanisms and Challenges

Brain Sciences
Background/Objectives: Non-response to initial treatment options for major depressive disorder (MDD) is a common clinical challenge with profound deleterious impacts for affected patients.
Michael J. Lucido, Boadie W. Dunlop
doaj   +1 more source

Pharmacology of novel psychoactive substances [PDF]

, 2016
This PhD work consists of an in vitro and in vivo part. In the in vivo part, we investigated the role of dopamine in the acute clinical effects of 3,4-methylenedioxymethamphetamine (MDMA, “ecstasy”) in healthy human subjects.
Rickli, Anna
core   +1 more source

Neuro‐Immune Crosstalk: Molecular Mechanisms, Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo, Hui Liu, Yu‐Jing Song, Jian‐Hua Wang, Danfeng Liu, Zhi‐Wei Zheng, Jia‐Jun Li, Boya Li, An Song, Wei He, Lei‐Lei Yang, Shuo Wang   +11 more
wiley   +1 more source

Screening for biogenic amines production by lactobacillus species and development of functional food, tea curd [PDF]

, 2013
Biogenic amines (BA) are substances with one or more than one amine groups.BA is organic, basic nitrogenous compounds of low molecular weight. Biogenic amines (BA) are natural toxins.
Sahoo , Banishree
core  

Neurotransmitters and Immunity: Molecular Mechanisms, Biological Functions, Diseases, and Potential Therapeutic Targets

MedComm, Volume 6, Issue 12, December 2025.
Role of neurotransmitters in multiple pathological processes. Various neurotransmitters, including ACh, EPI, NE, 5‐HT, histamine, DA, glutamate, GABA, and neuropeptides participate in regulating key pathological events, including tumor proliferation, tumor migration, remodeling of the immune microenvironment, and the development of NDDs and ...
Gege Li, Fangfang Li, Yang Tang, Siyu Guo, Yihan Yao, Yuan Fang, Bicheng Zhang, Yu Jiang, Jing Wang, Dang Wu, Jianxia Cheng, Zhihui Huang, Zengfeng Xin, Ting Zhang   +13 more
wiley   +1 more source

Oral KDS2010, a Monoamine Oxidase‐B (MAO‐B) Inhibitor, Slows the Deterioration of Motor Coordination in Genetic SCA1 Models by Inhibiting Astrocytic MAO‐B‐Mediated Inflammation

Journal of Neurochemistry, Volume 169, Issue 12, December 2025.
Astrocytes play a critical role in neurodegenerative disease pathology by modulating inflammatory responses and clearing toxic protein aggregates. In this study, we evaluated the therapeutic potential of KDS2010, a reversible and selective MAO‐B inhibitor, in a mouse model of spinocerebellar ataxia type 1 (SCA1).
Dong Ho Woo, Ju‐Hyun Jeon, Hye‐Jin Ryu, Gyeong Min Lee, Hye‐Won Lim, Ki Duk Park, Kwang Lae Hoe, Sang Dal Rhee   +7 more
wiley   +1 more source

FLUORESCENCE HISTOCHEMISTRY OF BIOGENIC MONOAMINES A STUDY OF THE CAPACITY OF VARIOUS CARBONYL COMPOUNDS TO FORM FLUOROPHORES WITH BIOGENIC MONOAMINES IN GAS PHASE REACTIONS [PDF]

Journal of Histochemistry & Cytochemistry, 1972
The capacity of biogenic amines to form fluorophores in histochemical gas phase reactions has been tested with 20 compounds having a carbonyl group (> C = O) as a common characteristic. Significant visible fluorescence was induced from catecholamines and indolamines with aldehydes, ketones, α-keto acids and carboxylic acids, suggesting that all of ...
S, Axelsson, A, Björklund, O, Lindvall
openaire   +2 more sources

Vesicular Amine Transporter VMAT2 in the Rat Ileum: from Principal Mechanism to Clinical Applications [PDF]

, 2015
Besides the role of a classical neurotransmitter, histamine plays a key role in the immune/inflammatory processes in the gastrointestinal tract. Specific transport proteins pack the amine neurotransmitters into vesicles so that their release can be ...
Stoyanova, I.I.
core   +1 more source

Monoamine transporter and receptor interaction profiles of novel psychoactive substances: para-halogenated amphetamines and pyrovalerone cathinones [PDF]

, 2015
The pharmacology of novel psychoactive substances is mostly unknown. We evaluated the transporter and receptor interaction profiles of a series of para-(4)-substituted amphetamines and pyrovalerone cathinones.
Hoener, Marius C., Liechti, Matthias E., Rickli, Anna   +2 more
core   +1 more source