Results 51 to 60 of about 5,403 (178)

Histamine in Brazilian Foods: A Comprehensive Review of Occurrence and Risk Assessment for Intoxication and Intolerance

open access: yesFood Science &Nutrition, Volume 13, Issue 11, November 2025.
Even though histamine plays an important role in human health, it has been associated with food intoxication and intolerance episodes. The most relevant, current state of knowledge regarding histamine's biochemical and health aspects is provided. Histamine levels are provided for 17 food groups, including 335 food types and 11,437 samples, allowing ...
Maria Beatriz A. Gloria   +6 more
wiley   +1 more source

Relationships between the level of psycho-emotional stress and the content of biogenic amines, sex and thyroid hormones in male population of Arkhangelsk

open access: yesСибирский научный медицинский журнал
The article presents the relationship between the level of psycho-emotional stress and the content of biogenic amines, sex and thyroid hormones in healthy men in the city of Arkhangelsk, taking into account the change of seasons.Material and methods. The
I. N. Molodovskaya   +4 more
doaj   +1 more source

Novel roles for biogenic monoamines: from monoamines in transglutaminase‐mediated post‐translational protein modification to monoaminylation deregulation diseases [PDF]

open access: yesThe FEBS Journal, 2011
Functional protein serotonylation is a newly recognized post‐translational modification with the primary biogenic monoamine (PBMA) serotonin (5‐HT). This covalent protein modification is catalyzed by transglutaminases (TGs) and, for example, acts in the constitutive activation of small GTPases.
Walther, D.   +2 more
openaire   +3 more sources

Conditioned place preference and locomotor activity in response to methylphenidate, amphetamine and cocaine in mice lacking dopamine D4 receptors [PDF]

open access: yes, 2010
Methylphenidate (MP) and amphetamine (AMPH) are the most frequently prescribed medications for the treatment of attention-deficit/hyperactivity disorder (ADHD).
Bermeo, C.   +6 more
core   +1 more source

Design, Synthesis, Biological Evaluation, and In Silico Study of Tetrahydropyridines as Prospective Monoamine Oxidase Inhibitors

open access: yesChemistryOpen, Volume 14, Issue 10, October 2025.
This work investigates the selective inhibition of MAO enzymes by varying the substitution of electron‐withdrawing and donating groups on the phenyl rings of tetrahydropyridines (4 a–4 o). Compounds 4 l and 4 n exhibit promising IC50 values of 0.40±0.05 and 1.01±0.03 μM against MAO‐A and MAO‐B, respectively.
Obaid ur Rehman Khan   +10 more
wiley   +1 more source

Altered brainstem responses to modafinil in schizophrenia: implications for adjunctive treatment of cognition. [PDF]

open access: yes, 2018
Candidate pro-cognitive drugs for schizophrenia targeting several neurochemical systems have consistently failed to demonstrate robust efficacy. It remains untested whether concurrent antipsychotic medications exert pharmacodynamic interactions that ...
Carter, Cameron S   +3 more
core   +3 more sources

Triggers, Protectors, and Predictors in Episodic Migraine. [PDF]

open access: yes, 2018
PURPOSE OF REVIEW: A wide variety of triggers prompt attacks in episodic migraine. Although experimental triggers such as glyceryl trinitrate reliably produce migraine, natural triggers are much less predictable and vary in importance between individuals.
Marmura, Michael J.
core   +1 more source

Mitochondrial targets in ischaemic heart disease and heart failure, and their potential for a more efficient clinical translation. A scientific statement of the ESC Working Group on Cellular Biology of the Heart and the ESC Working Group on Myocardial Function

open access: yesEuropean Journal of Heart Failure, Volume 27, Issue 9, Page 1720-1736, September 2025.
Improving clinical translation of mitoprotective therapies. 31P MRI, phosphorus‐31 magnetic resonance imaging; hiPSC‐CM, human‐induced pluripotent stem cell‐derived cardiomyocyte; IHD, ischaemic heart disease. Abstract Acute myocardial infarction (MI) remains a major cause of death and disability worldwide.
Melanie Paillard   +29 more
wiley   +1 more source

Benzo[b]tiophen-3-ol derivatives as effective inhibitors of human monoamine oxidase: design, synthesis, and biological activity [PDF]

open access: yes, 2019
A series of benzo[b]thiophen-3-ols were synthesised and investigated as potential human monoamine oxidase (hMAO) inhibitors in vitro as well as ex vivo in rat cortex synaptosomes by means of evaluation of 3,4-dihydroxyphenylacetic acid/dopamine (DOPAC/DA)
Alcaro, Stefano   +13 more
core   +1 more source

Bioactive Potential and Health Benefits of Trigonella foenum‐graecum L.: A Comprehensive Review

open access: yesFood Science &Nutrition, Volume 13, Issue 9, September 2025.
Trigonella foenum‐graecum seeds contain mucilaginous fiber, which will tie bile acids and lower fat absorption and cholesterol. These bioactive constituents contribute to fenugreek's antioxidant, anti‐inflammatory, antinociceptive, antidiabetic, hypocholesterolemic, gastroprotective, antirheumatic, and antimicrobial activities. ABSTRACT Fenugreek seeds
Hassnain Akhtar   +10 more
wiley   +1 more source

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