Results 71 to 80 of about 5,403 (178)

Monoaminergic control of spinal locomotor networks in SOD1G93A newborn mice [PDF]

open access: yes, 2013
Mutations in the gene that encodes Cu/Zn-superoxide dismutase (SOD1) are the cause of approximately 20% of familial forms of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease characterized by the progressive loss of motor neurons ...
Grégory Barrière   +4 more
core   +4 more sources

Acute Effects of Four Major Trace Amines on Zebrafish Behavioral, Neurochemical, and Neuroendocrine Responses

open access: yesJournal of Neurochemistry, Volume 169, Issue 6, June 2025.
A trace amine beta‐phenylethylamine is anxiolytic and reduces brain acetylcholine at 12 μg/L, but elevates anxiety and cortisol levels at 1000 μg/L. Acute tryptamine at 7 mg/L is anxiogenic, reduces shoaling and social interaction, but elevates brain acetylcholine and cortisol levels. Acute tyramine at 15 μg/L, and octopamine at 125, 500, and 1500 μg/L,
Thalia M. Quintanilha   +10 more
wiley   +1 more source

Preserving Neuronal Chemical Messengers: Heat Stabilization Versus Snap Freezing for Improved MALDI Mass Spectrometry Imaging of Brain Tissues

open access: yesJournal of Neurochemistry, Volume 169, Issue 6, June 2025.
Rapid heat stabilization of brain tissue preserves the natural levels and spatial distribution of neurotransmitters and neuropeptides better than traditional snap freezing. Using matrix‐assisted laser desorption/ionization mass spectrometry imaging (MALDI‐MSI), we show that heat stabilization effectively prevents postmortem enzymatic degradation ...
Emanuela Salviati   +7 more
wiley   +1 more source

α-Methyl derivatives of biogenic amines as inhibitors of monoamine oxidase

open access: yesJournal of Pharmacy and Pharmacology, 1976
AbstractThe values of Km app and Vmax for three natural substrates of monoamine oxidase have been determined at various stages in the isolation of the enzyme from rat liver tissue. The results are consistent with the presence in the enzyme preparation of at least two distinct molecular forms of the enzyme.Using the α-methyl derivatives of the natural ...
F, Inoue, J B, Robinson, S A, Stansfield
openaire   +2 more sources

Neurotoxicity induced by mephedrone: an up-to-date review [PDF]

open access: yes, 2017
BACKGROUND: Mephedrone is a β-ketoamphetamine belonging to the family of synthetic cathinones, an emerging class of designer drugs known for their hallucinogenic and psychostimulant properties as well as for their abuse potential.
Busardo', FRANCESCO PAOLO   +6 more
core   +1 more source

Octopamine underlies the counter-regulatory response to a glucose deficit in honeybees (Apis mellifera) [PDF]

open access: yes, 2017
An animal’s internal state is a critical parameter required for adaptation to a given environment. An important aspect of an animal’s internal state is the energy state that is adjusted to the needs of an animal by energy homeostasis.
Buckemüller, Christina   +5 more
core   +2 more sources

Characterization of Vesicular Monoamine Transporter 2 and its role in Parkinson\u27s Disease Pathogenesis using Drosophila [PDF]

open access: yes, 2016
Parkinson’s disease (PD) is a progressive neurodegenerative disorder caused by the selective loss of the dopaminergic neurons in the Substantia nigra pars compacta region of the brain.
Tito, Antonio Joel, Jr., Zhang, Sheng
core   +1 more source

Molecular biology of amitraz resistance in cattle ticks of the genus Rhipicephalus [PDF]

open access: yes, 2018
Amitraz is an important product for the control of cattle ticks around the world. In comparison with other products for the control of ticks, it is quite affordable and it has a rapid knock-down effect.
Berry, Christina M.   +5 more
core   +1 more source

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