Results 121 to 130 of about 568 (157)

Bioguided isolation of antiplasmodial secondary metabolites from Mill. (Lauraceae)

Zeitschrift für Naturforschung C, 2021
**Abstract** The antiplasmodium assay-guided investigation of the roots, stem bark, and leaves ofPersea americanaMill. led to the isolation of a new fatty alcohol, perseatriol (1), along with six known compounds (2–7). Their structures were elucidated based on the analysis of their NMR and MS data.
Waleguele, Christine Claire, Tchuente Tchuenmogne, Marthe Aimée, Fotsing Fongang, Yannick Stéphane, Ngatchou, Jules, Kezetas Bankeu, Jean Jules, Ngouela, Augustin Silvère, Tsamo, Etienne, Sewald, Norbert, Krause, Rui Werner Maçedo, Lenta, Bruno Ndjakou   +9 more
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Bioguided Fractionation and Isolation of an Antiplasmodial Saponin from the Roots of Nauclea xanthoxylon (A.Chev.) Aubrév. (Rubiaceae)

Chemistry & Biodiversity, 2023
AbstractThe root extract of Nauclea xanthoxylon (A.Chev.) Aubrév. displayed significant 50 % inhibition concentration (IC50s) of 0.57 and 1.26 μg/mL against chloroquine resistant and sensitive Plasmodium falciparum (Pf) Dd2 and 3D7 strains, respectively.
Nangmou Nkouayeb, Brice Maxime, Maza Djomkam, Hermine Laure, Tabekoueng, Georges Bellier, Dongmo Tekapi Tsopgni, Willifred, Mbahbou Bitchagno, Gabin Thierry, Mbock, Michel Arnaud, Gounoue Kamkumo, Raceline, Frese, Marcel, Ndjakou Lenta, Bruno, Ngouela, Silvere Augustin, Sewald, Norbert, Azebaze, Anatole Guy Blaise   +11 more
openaire   +2 more sources

Bioguided isolation, identification and activity evaluation of antifungal compounds from Acorus tatarinowii Schott

Journal of Ethnopharmacology, 2020
As a traditional folk medicine, Acorus tatarinowii Schott was used to treat digestive diseases, such as diarrhea, which may be related to Candida albicans infection; however according to literature surveys, there have been few studies of A. tatarinowii focusing on its antimicrobial activity, and almost all describe investigations using crude extracts ...
Zhao-Jie, Wang, Yan-Yan, Zhu, Xin, Yi, Zhong-Shun, Zhou, Ying-Jie, He, Ying, Zhou, Zi-Heng, Qi, Dan-Ni, Jin, Li-Xing, Zhao, Xiao-Dong, Luo   +9 more
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Bioguided fractionation and isolation of esculentoside P from Phytolacca americana L.

Industrial Crops and Products, 2013
Abstract Various solvent extracts from different organs of Phytolacca americana L. were tested for their acaricidal activities against female carmine spider mite [ Tetranychus cinnabarinus (Boisduval)] adults by slide-dip bioassay. The acetone extracts of roots with mortality rates of 95.72% and 100.00% at 2.5 mg/mL were more active than those of ...
Li-Juan Ding, Wei Ding, Yong-Qiang Zhang, Jin-Xiang Luo   +3 more
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Isolation of antileishmanial sterol from the fruits of Cassia fistula using bioguided fractionation

Phytotherapy Research, 2007
AbstractNatural products represent a rich source of new chemical entities for the development of drugs for neglected diseases. Leishmaniasis still afflicts the poorest populations in the world, with 12 million cases worldwide. This work analysed crude extracts and fractions from the fruits of Cassia fistula against the most dramatic and fatal disease ...
Patrícia, Sartorelli, Samanta P, Andrade, Márcia S C, Melhem, Frederico O, Prado, André G, Tempone   +4 more
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Bioguided isolation of a selective compound from Calea phyllolepis leaves against breast cancer cells

Basic & Clinical Pharmacology & Toxicology, 2021
AbstractPlants of the Calea genus have been reported to contain lipophilic compounds, such as sesquiterpene lactones, with cytotoxic effect against different cancer cell lines. The aim of this manuscript was to investigate the chemical profile and cytotoxic activity of different fractions from Calea phylolepis leaves on different human cancer cell ...
Rodrigo Bitencourt Da Rosa, Guilherme Borsoi, Lucas Umpierre Conter, Cleverson Feistel, Anderson Leonardo Gottems, Flávio Henrique Reginatto, Ivana Grivicich, Alexandre De Barros Falcão Ferraz   +7 more
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Bioguided isolation, identification and bioactivity evaluation of anti-fatigue constituents from Schizophyllum commune

Fitoterapia
This study aims to clarify the specific anti-fatigue components of Schizophyllum commune (S.commune) and analyze its potential anti-fatigue mechanism. The main anti-fatigue active ingredient of S.commune was locked in n-butanol extract (SPE-n) by activity evaluation.
Hao, Chen, Qianzhen, Wu, Kaili, Xuan, Wenqiang, Guo, Kunfeng, Zhang, Yuanyuan, Wang, Zhenzhen, Dai, Rong, Sheng, Huaqi, He, Yuzhe, Huang, Yan, Chen   +10 more
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Bioguided isolation of angiotensin‐converting enzyme inhibitors from the seeds of Plantago asiatica L.

Phytotherapy Research, 2010
AbstractEthanolic extract of the seeds of Plantago asiatica L. showed significant inhibitory activity of angiotensin‐converting enzyme (ACE) determined by monitoring the transformation from a substrate hippuryl‐histidyl‐leucine (HHL) to the product hippuric acid (HA) in vitro using an UPLC‐MS method.
Fang, Geng, Li, Yang, Guixin, Chou, Zhengtao, Wang   +3 more
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Bioguided Isolation and Identification of the Nonvolatile Antioxidant Compounds from Fennel (Foeniculum vulgare Mill.) Waste

Journal of Agricultural and Food Chemistry, 2004
A bioguided isolation of an aqueous extract of fennel waste led to the isolation of 12 major phenolic compounds. Liquid chromatography coupled to atmospheric pressure chemical ionization mass spectrometry (LC/UV/APCI-MS) combined with spectroscopic methods (NMR) was used for compound identification.
Parejo, I., Viladomat, F., Bastida, J., Schmeda-Hirschmann, G., Burillo, J., Codina, C.   +5 more
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Bioguided Isolation and Antiproliferative Activity of Constituents fromSmilax korthalsiiA.D.C. Leaves

Journal of the Chinese Chemical Society, 2016
AbstractEthyl acetate extract ofSmilax korthalsiiA.D.C. leaves exhibited antiproliferative activity on leukaemia carcinoma K562, hepatic liver cancer cells WRL and colorectal carcinoma with IC50of 125.20, 46.10 and 160.00 μM respectively. Isolation of the bioactive ethyl acetate extract ofSmilax korthalsiiA.D.C.
Abdulmumeen A. Hamid, Olapeju O. Aiyelaagbe, Arvind S. Negi, Suaib Luqman, Fatima Kaneez   +4 more
openaire   +1 more source