Results 71 to 80 of about 280,000 (306)
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Freedom in bioinformatics [PDF]
1 Institut de Biologie Integrative et des Systemes, Universite Laval, Quebec City, QC, Canada 2 Departement de Biochimie, de Microbiologie et de Bio-informatique, Faculte des Sciences et de Genie, Universite Laval, Quebec City, QC, Canada 3 Centre de Recherche de l’Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Quebec City, QC ...
Antony T Vincent +5 more
openaire +3 more sources
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Determination of Physicochemical Properties of Human Immunoglobulin G- Fc Fragment by Bioinformatic
Introduction: Immunoglobulins (Igs) are defensive glycoproteins specifically recognize and destroy pathogens. Immunoglobulin G (IgG) is most abundant Ig in serum has important protective role against infections. Fragment of crystallizable (Fc) in IgG has
Soheyla Rohani, Fatemeh Hajighasemi
doaj
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
biomisc: collection of miscellaneous command line bioinformatic scripts
collection of miscellaneous command line bioinformatic ...
Olga Tsiouri
core +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Bioinformatic pipeline followed for annotation of unigenes.
Bioinformatic pipeline followed for annotation of unigenes.
Nisha Joy (384872) +3 more
core +1 more source
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Flowchart for the process of bioinformatic analysis.
Flowchart for the process of bioinformatic analysis.
Xiaoming Wei (191334) +11 more
core +1 more source

