Results 91 to 100 of about 1,060,544 (307)

Community development, implementation, and assessment of a NIBLSE bioinformatics sequence similarity learning resource.

open access: yesPLoS ONE, 2021
As powerful computational tools and 'big data' transform the biological sciences, bioinformatics training is becoming necessary to prepare the next generation of life scientists. Furthermore, because the tools and resources employed in bioinformatics are
Adam J Kleinschmit   +12 more
doaj   +1 more source

Introduction to Bioinformatics [PDF]

open access: yesarXiv, 2009
Bioinformatics is a new discipline that addresses the need to manage and interpret the data that in the past decade was massively generated by genomic research. This discipline represents the convergence of genomics, biotechnology and information technology, and encompasses analysis and interpretation of data, modeling of biological phenomena, and ...
arxiv  

Lessons learned to boost a bioinformatics knowledge base reusability, the Bgee experience [PDF]

open access: yesarXiv, 2023
Background, enhancing interoperability of bioinformatics knowledge bases is a high priority requirement to maximize data reusability, and thus increase their utility such as the return on investment for biomedical research. A knowledge base may provide useful information for life scientists and other knowledge bases, but it only acquires exchange value
arxiv  

The accumulation of myeloid‐derived suppressor cells participates in abdominal infection‐induced tumor progression through the PD‐L1/PD‐1 axis

open access: yesMolecular Oncology, EarlyView.
This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang   +10 more
wiley   +1 more source

Bioinformatics approach to enhance the undergraduate biology students’ understanding of plant terpenoid

open access: yesJPBI (Jurnal Pendidikan Biologi Indonesia)
Plant metabolite compounds have been applied on plant cellular metabolism, produces organic and inorganic compounds, primary and secondary bioactive molecules, such as glucose, amino acids, fat acids, alkaloids, flavonoids, and terpenoids. Undergraduate
Risanti Dhaniaputri   +2 more
doaj   +1 more source

Unraveling epigenetic heterogeneity across gastrointestinal adenocarcinomas through a standardized analytical framework

open access: yesMolecular Oncology, EarlyView.
This study shows that patients with gastrointestinal adenocarcinomas can be stratified into six distinct subtypes based on genome‐scale DNA methylation profiling. This stratification, achieved using a robust analytical framework, aligns with established tumor characteristics and holds potential to support prognostication.
Rita Pinto   +3 more
wiley   +1 more source

Proceedings of the 13th Workshop on Algorithms in Bioinformatics (WABI2013) [PDF]

open access: yesarXiv, 2013
These are the proceedings of the 13th Workshop on Algorithms in Bioinformatics, WABI2013, which was held September 2-4 2013 in Sophia Antipolis, France. All manuscripts were peer reviewed by the WABI2013 program committee and external reviewers.
arxiv  

SKA1 promotes oncogenic properties in oral dysplasia and oral squamous cell carcinoma, and augments resistance to radiotherapy

open access: yesMolecular Oncology, EarlyView.
The mitosis‐related gene SKA1 was among 629 genes consistently dysregulated in OSCC across nine public gene expression datasets. In OSCC cell lines, SKA1 promoted proliferation and migration, enhanced radioresistance, and reduced radiation‐induced senescence.
Alexander Michael Grandits   +7 more
wiley   +1 more source

Undergraduate Bioinformatics Workshops Provide Perceived Skills

open access: yesJournal of Microbiology & Biology Education, 2014
Bioinformatics is becoming an important part of undergraduate curriculum, but expertise and well-evaluated teaching materials may not be available on every campus. Here, a guest speaker was utilized to introduce bioinformatics and web-available exercises
Robin Herlands Cresiski
doaj   +1 more source

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