Results 211 to 220 of about 1,243,490 (281)

Enhancing Organic Light‐Emitting Diode Performance Using Naturally Derived Diatomite: A Cost‐Effective and Eco‐Friendly Strategy

Advanced Optical Materials, EarlyView.
Diatomite‐based light extraction structures enable enhanced photon outcoupling through multi‐angle scattering and far‐field redistribution. By harnessing the unique scattering behavior of diatomite, this approach introduces randomly oriented scattering centers that effectively reshape internal light propagation.
Chang Min Lee, Ki Ha Min, Donghyun Choi, Yeong Beom Kim, Insung Ha, Mengdi Fu, Hyun Jae Lee, Ezhakudiyan Ravindran, Chul Hoon Kim, Jeongho Lee, Kyoung‐Ho Kim, Seung Pil Pack, Seung Yoon Ryu   +12 more
wiley   +1 more source

Integrated analysis of bioinformatics, mendelian randomization, and experimental validation reveals novel diagnostic and therapeutic targets for osteoarthritis: progesterone as a potential therapeutic agent [PDF]

Ziyu Weng, Chenzhong Wang, Bo Liu, Yi Yang, Yueqi Zhang, Chi Zhang   +5 more
openalex   +1 more source

Opportunities and considerations for using artificial intelligence in bioinformatics education. [PDF]

Bioinform Adv
Piccolo SR, Nathan A, Brazas MD, Kandpal M, Miró-Herrans AT, Kleinschmit AJ, McClatchy S, Mutheiwana P, Nikolic D, Gallo LI, Julius RS, Lloret-Llinares M, Mulder N, Presgraves D, Shewaramani S, Xool-Tamayo J, Chain FJJ, Sanchez Guerrero SA.   +17 more
europepmc   +1 more source

Multitasking Smart Intestinal Capsule Robot: A Cutting‐Edge Platform for Sampling, Diagnosis, and Therapy

Advanced Robotics Research, EarlyView.
Gut microbiota and biomarkers are linked to diseases like neurological disorders and metabolic syndromes. Ingestible capsule robots enable minimally invasive gut health assessment. This article proposes a promising direction for the advancement of capsule robots, integrating in situ sampling, real‐time diagnostics, and personalized therapy.
Xizong Chen, Libing Huang, Lei Ren, Miao Wang   +3 more
wiley   +1 more source

sc2DAT: workflow for targeting tumor subpopulations of single cells. [PDF]

Bioinform Adv
Marino GB, Byrd AI, Ahmed N, Clarke DJB, Ma'ayan A.   +4 more
europepmc   +1 more source

Distinguishing highly similar gene isoforms with a clustering-based bioinformatics analysis of PacBio single-molecule long reads [PDF]

, 2016
Ma Liang, Castle Raley, Xin Zheng, Geetha Kutty, Emile Gogineni, Brad T. Sherman, Qiang Sun, Xiongfong Chen, Thomas Skelly, Kristine Jones, Robert M. Stephens, Bin Zhou, William Lau, Calvin A. Johnson, Tomozumi Imamichi, Minkang Jiang, Robin Dewar, Richard A. Lempicki, Bao Tran, Joseph A. Kovacs, Da Wei Huang   +20 more
openalex   +1 more source

ST6GAL1‐Mediated Sialylation Stabilizes PD‐L1 and Drives Immunosuppressive Tumor Microenvironment in Colorectal Cancer

Advanced Science, EarlyView.
ST6GAL1 plays a critical role in tumor progression and immune regulation in colorectal cancer (CRC). Its depletion significantly suppresses the malignant phenotype of CRC cells and enhances the efficacy of anti‐PD‐L1 therapy. High ST6GAL1 expression promotes an immune‐activated tumor microenvironment (TME), characterized by increased infiltration of ...
Ximo Xu, Jingyi Liu, Wei Qin, Chengsheng Ding, Zhenghao Cai, Duohuo Shu, Hao Zhong, Yanyan Hu, Mengqin Yu, Leqi Zhou, Jianwen Li, Minhua Zheng, Bin Li, Sen Zhang, Xiao Yang, Bo Feng   +15 more
wiley   +1 more source

XBP1s Mediates Cross‐resistance to Combination Treatment of CDK4/6 Inhibitors plus Endocrine Therapy in Breast Cancer

Advanced Science, EarlyView.
Elevated spliced form of X‐box–binding protein 1 (XBP1) correlates with unfavorable responses to endocrine therapy plus CDK4/6 inhibitors in HR+/HER2− advanced breast cancer. XBP1s facilitates cell proliferation and G1/S transition by transcriptionally activating SND1, thereby activating the E2F1 pathway.
Yuting Sang, Shiyang Liu, Xujie Zhou, Weiru Chi, Min Xiong, Ming Chen, Hengyu Ren, Douwaner Liu, Liyi Zhang, Jingyan Xue, Yayun Chi, Jiong Wu   +11 more
wiley   +1 more source

Excessive DNA Double‐Strand Breaks–Associated 3D Genome Reorganization Contributes to Neural Tube Defects with Folate Deficiency

Advanced Science, EarlyView.
Neural tube defects (NTDs) are among the most common congenital malformations. However, the underlying etiology and mechanism remain elusive. Here, the role of DNA double‐strand breaks (DSBs) in 3D genome organization within the NTDs with folate deficiency is reported.
Ting Zhang, Lin Lin, Jianting Li, Caihua Li, Shengjun Liang, Xuemei Bai, Fang Wang, Yihua Bao, Dan Guo, Xiaochen Bo, Hao Li, Hebing Chen, Qiu Xie   +12 more
wiley   +1 more source

Multiomics Analyses Reveal an Essential Role of Tryptophan in Treatment of csDMARDs in Rheumatoid Arthritis

Advanced Science, EarlyView.
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian, Jing Zhu, Jianhong Wu, Yan Zhang, Jianghua Chen, Huan Wang, Hengyan Liu, Ke Xu, Jiaxin Huang, Xiaoting Zhu, Yuanli Wei, Shilin Li, Tingting Wang, Xuan Huang, Qinghua Zou, Jie Zhang, Jiang Su, Xinming Du, Yaping Lu, Tianci Zhou, Yingtong Zhou, Minglong Tang, Bin Li, Xue Zhou, Qihao Wei, Qiulong Yan, Fanxin Zeng   +26 more
wiley   +1 more source