Results 211 to 220 of about 1,268,351 (323)

Exploring Ligand Effects in the Selective Catalytic Dehydrogenative Borylation of Alkynes with Aluminum

open access: yesAdvanced Synthesis &Catalysis, EarlyView.
Proper selection of a modified guanidinato ligand allows for the selective catalytic dehydroborylation of terminal alkynes by an air‐stable aluminum complex. A plausible reaction pathway is suggested based on DFT studies, where the auxiliary substituent of the guanidinato ligand actively participates in the activation of the σ CH bond.
Carlos Ginés   +6 more
wiley   +1 more source

Challenges and Future Directions in Assessing the Quality and Completeness of Advanced Materials Safety Data for Re‐Usability: A Position Paper From the Nanosafety Community

open access: yesAdvanced Sustainable Systems, EarlyView.
Nanosafety data provide a guiding example for establishing best practices in data management, aligning with FAIR principles and quality criteria. This review explores existing quality assessment approaches for reliability, relevance, and completeness, emphasizing the need for harmonization and adaptation to nanomaterials and advanced materials. The aim
Verónica I. Dumit   +43 more
wiley   +1 more source

Phase‐Separation of YAP Mediates AJUBA Super Enhancer Activation to Promote Aberrant Mitosis in Breast Cancer

open access: yesAdvanced Science, EarlyView.
YAP undergoes phase separation to activate the AJUBA super‐enhancer, driving aberrant mitosis through spindle checkpoint dysregulation in breast cancer. This study uncovers a mechanistic link between YAP condensates, super‐enhancer activation, and aneuploidy formation.
Rui Zhang   +8 more
wiley   +1 more source

Multiomics Analyses Reveal an Essential Role of Tryptophan in Treatment of csDMARDs in Rheumatoid Arthritis

open access: yesAdvanced Science, EarlyView.
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian   +26 more
wiley   +1 more source

ELViS: an R package for estimating copy number levels of viral genomic segments at base-resolution. [PDF]

open access: yesBioinformatics
Lee JY   +5 more
europepmc   +1 more source

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