Results 261 to 270 of about 1,243,490 (281)

SBMLtoOdin and Menelmacar: interactive visualisation of systems biology models for expert and non-expert audiences. [PDF]

Bioinformatics
Lorenz LJ, Andréoletti A, Nguyen TVN, Hermjakob H, FitzJohn RG, Malik Sheriff RS, Lees JA.   +6 more
europepmc   +1 more source

Actors and higher order functions : A Comparative Study of Parallel Programming Language Support for Bioinformatics

, 2014
Staffan Arvidsson
openalex   +1 more source

Subventricular Zone‐on‐a‐Chip: A Model to Study Neurogenesis Disruption in Neonatal Intraventricular Hemorrhage

Advanced Science, EarlyView.
A human subventricular zone‐on‐a‐chip is developed to model intraventricular hemorrhage (IVH) in preterm infants. This platform enables the study of inflammation‐driven neurogenic disruption. Exposure to hemorrhagic cerebrospinal fluid and red blood cell lysate activated inflammatory pathways, with IL1B emerging as a key mediator.
Laura Nicoleti Zamproni, Begüm Gökçe, Magnus Gram, Coco Holliday, Aylin Sendemir, Marimélia Aparecida Porcionatto, Anna Herland   +6 more
wiley   +1 more source

Genomic Insights into Antimicrobial Resistance in Salmonella typhi: A Bioinformatics-Based Surveillance Model from Public Datasets with Implications for Resource-Limited Settings

Ehizokhale Jude Usiabulu, Onolunosen Abel Abhadionmhen, Husseni Iduku   +2 more
openalex   +2 more sources

TBC1D22B Regulates ER‐to‐Golgi Trafficking via RAB1B Inactivation and Promotes Oncogenic Programs in Breast Cancer

Advanced Science, EarlyView.
TBC1D22B, a Golgi‐localized RabGAP linked to poor prognosis in breast cancer, inhibits ER‐to‐Golgi transport via RAB1B inactivation. This disrupts secretion, drives oncogenic transcriptional reprogramming, and promotes tumor growth. These findings indicate that TBC1D22B connects membrane trafficking to transcriptional control and cancer progression ...
Flavia Martino, Mariadomenica Lupi, Alessandra Murabito, Fabio Bedin, Giulia Villari, Linda Andreoli, Stefano Freddi, Bronislava Matoskova, Rosa Pennisi, Stella Fontana, Amir Fardin, Gaelle Boncompain, Franck Perez, Federico Bussolino, Alessandro Cuomo, Sara Sigismund, Letizia Lanzetti   +16 more
wiley   +1 more source

BTS: a scalable Bayesian Tissue Score for prioritizing GWAS variants and their functional contexts across >1000s of omics datasets. [PDF]

Bioinformatics
Kuksa PP, Ionita M, Carter L, Cifello J, Gangadharan P, Clark K, Valladares O, Leung YY, Wang LS.   +8 more
europepmc   +1 more source

A bioinformatics pipeline for Screening Nodule-specific Cysteine-Rich (NCR) like peptides from Trigonella foenum-graecum and Medicago truncatula genomes

Sneha Bidvi, Rajendra Choure, R.S. Jadhav, Manohar V. Padul, Sayli Mandavkar, Akshada Bhadane, Mrunal Posam   +6 more
openalex   +1 more source

Calhm6 Governs Macrophage Polarization Through Chp1‐Camk4‐Creb1 Axis and Ectosomal Delivery in Inflammatory Responses

Advanced Science, EarlyView.
Calhm6 drives M2 macrophage polarization via the Chp1‐Camk4‐Creb1 axis, suppressing inflammation through calcium‐dependent ectosomal delivery. Calhm6 deficiency enhances M1 responses, boosting bactericidal activity but exacerbating tissue damage. LPS/IFNγ upregulate Calhm6 via Irf1, while IL‐4/Stat6 inhibits it, balancing immune outcomes.
Yanlong Xin, Xiaofan Xiong, Yan Zhang, Siyu Zhang, Shuting Zhang, Yu Yang, Yingxue Liang, Lulu Zang, Xi Chen, Wenjuan Li, Issam Halalmeh, Rui Zhou, Zongfang Li, Haowen Liu, Jing Geng   +14 more
wiley   +1 more source

An interpretable alphabet for local protein structure search based on amino acid neighborhoods. [PDF]

Bioinformatics
Zerefa S, Cool J, Singh P, Petti S.
europepmc   +1 more source

Physiological pH Transition‐Driven Protein Corona Dynamics Regulate Cellular Uptake and Inflammatory Responses of Silica Nanoparticles

Advanced Science, EarlyView.
Physiological pH transitions modulate protein corona dynamics on nanoparticles, altering their cellular uptake and inflammatory responses. Acidic pHs enhance protein adsorption, induce structural changes, and promote cellular uptake. Simultaneously, inflammatory responses are reduced due to altered protein composition, including decreased ...
Yuting Ge, Fangqin Fu, Yu Gao, Tianchang He, Volker Mailänder, Daniel Crespy, Katharina Landfester, Shuai Jiang   +7 more
wiley   +1 more source