Results 31 to 40 of about 782,783 (305)

Aptamer Bioinformatics [PDF]

International Journal of Molecular Sciences, 2017
Aptamers are short nucleic acid sequences capable of specific, high-affinity molecular binding. They are isolated via SELEX (Systematic Evolution of Ligands by Exponential Enrichment), an evolutionary process that involves iterative rounds of selection and amplification before sequencing and aptamer characterization.
Andrew Kinghorn, Lewis Fraser, Shaolin Liang, Simon Shiu, Julian Tanner   +4 more
openaire   +2 more sources

Leveraging network analytics to infer patient syndrome and identify causal genes in rare disease cases

BMC Genomics, 2017
Background Next-generation sequencing is widely used to identify disease-causing variants in patients with rare genetic disorders. Identifying those variants from whole-genome or exome data can be both scientifically challenging and time consuming.
Andreas Krämer, Sohela Shah, Robert Anthony Rebres, Susan Tang, Daniel Rene Richards   +4 more
doaj   +1 more source

The Third Annual Meeting of the European Virus Bioinformatics Center [PDF]

, 2019
The Third Annual Meeting of the European Virus Bioinformatics Center (EVBC) took place in Glasgow, United Kingdom, 28–29 March 2019. Virus bioinformatics has become central to virology research, and advances in bioinformatics have led to improved ...
Lycett, Samantha; id_orcid, Robertson, David, Dutilh, B.E., Escalera-Zamudio, M, V Thiel (7788257), Ibrahim, Bashar, Dutilh, Bas E., Clokie, MRJ, Julian Susat, EM Adriaenssens (7707755), Dutilh, Bas E, Escalera-Zamudio, Marina, Simmonds, P, Bas E. Dutilh, Abroi, Aare, Sicheritz, T, T Sicheritz (7788275), Adriaenssens, E.M., Jenna Nicole Kelly, Franziska Hufsky, JN Kelly (7788266), Kelly, Jenna Nicole, Theoretical Biology and Bioinformatics, Bashar Ibrahim, Deinhardt-Emmer, S., Modha, S, M Marz (7788278), Susat, J., Manja Marz, F Hufsky (7788239), Kevin Lamkiewicz, Bas E. Dutilh, Susat, Julian, Evelien M. Adriaenssens, Robertson, DL, Peter Simmonds, David L. Robertson, Deinhardt-Emmer, Stefanie, Robertson, David L, J Susat (7788272), Robertson, D.L., L Lu (4696135), Lu, Lu; id_orcid, Lu, L, Marina Escalera-Zamudio, Ibrahim, B, Lu, Lu, Thiel, V., Escalera-Zamudio, M., Clokie, Martha R. J., Kelly, JN, Thiel, V, Marz, Manja, Modha, S., Clokie, M.R., Lycett, Samantha, Lamkiewicz, Kevin, Samantha Lycett, Kelly, J.N., Volker Thiel, Thomas Sicheritz, Jenna Nicole Kelly, Hufsky, F, Marz, M, Robertson, David L., P Simmonds (7788254), Hufsky, F., Sicheritz, T., Abroi, A, BE Dutilh (7707779), Adriaenssens, Evelien M, S Deinhardt-Emmer (7788248), Sejal Modha, Deinhardt-Emmer, S, Thiel, Volker, Sub Bioinformatics, Lamkiewicz, K, Abroi, A., Evelien M. Adriaenssens, Susat, J, DL Robertson (7656881), Marz, M., Dutilh, BE, Stefanie Deinhardt-Emmer, David L. Robertson, Adriaenssens, Evelien M., Lycett, S., Lycett, S, Lu, L., Clokie, Martha R J, Simmonds, Peter, M Escalera-Zamudio (7788263), S Modha (7788245), Modha, Sejal, Lamkiewicz, K., Lu Lu, Sicheritz, Thomas, MRJ Clokie (7713161), Adriaenssens, EM, Hufsky, Franziska, S Lycett (7788251), A Abroi (7788260), K Lamkiewicz (7788269), Ibrahim, B., Martha R. J. Clokie, Aare Abroi, Martha R. J. Clokie, Simmonds, P., B Ibrahim (7788242)   +108 more
core   +1 more source

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho, Karim M. Soliman, Wisit Cheungpasitporn, Wannasit Wathanavasin, Ahmed Daoud, Ahmed I. Kamal, Balázs Szamosfalvi, Tibor Fülöp   +7 more
wiley   +1 more source

Freedom in bioinformatics [PDF]

Frontiers in Genetics, 2014
1 Institut de Biologie Integrative et des Systemes, Universite Laval, Quebec City, QC, Canada 2 Departement de Biochimie, de Microbiologie et de Bio-informatique, Faculte des Sciences et de Genie, Universite Laval, Quebec City, QC, Canada 3 Centre de Recherche de l’Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Quebec City, QC ...
Antony T Vincent, Antony T Vincent, Antony T Vincent, Steve J Charette, Steve J Charette, Steve J Charette   +5 more
doaj   +3 more sources

InCoB2014: Bioinformatics to tackle the data to knowledge challenge [PDF]

, 2014
Since 2006, the International Conference on Bioinformatics (InCoB) has been publishing selected papers in BMC Bioinformatics. Papers within the scope of the journal from the 13th InCoB July 31-2 August, 2014 in Sydney, Australia have been compiled in ...
Ranganathan, Shoba, Tan, Tin Wee, Schönbach, Christian, Ranganathan S., Shoba Ranganathan, Christian Schönbach, Schönbach C., Tin Tan, Tan T.W.   +8 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Streamlined and on-demand preparation of mRNA products on a universal integrated platform

Microsystems & Nanoengineering, 2023
Vaccines are used to protect human beings from various diseases. mRNA vaccines simplify the development process and reduce the production cost of conventional vaccines, making it possible to respond rapidly to acute and severe diseases, such as ...
Hongjuan Wei, Zhen Rong, Liyan Liu, Ye Sang, Jing Yang, Shengqi Wang   +5 more
doaj   +1 more source

Bioinformatics service reconciliation by heterogeneous schema transformation

, 2007
This paper focuses on the problem of bioinformatics service reconciliation in a generic and scalable manner so as to enhance interoperability in a highly evolving field.
Zamboulis, Lucas, Poulovassilis, Alexandra, Martin, Nigel   +2 more
core   +1 more source