Results 51 to 60 of about 1,289,019 (331)

Algebraic Comparison of Partial Lists in Bioinformatics [PDF]

, 2010
The outcome of a functional genomics pipeline is usually a partial list of genomic features, ranked by their relevance in modelling biological phenotype in terms of a classification or regression model.
A Gobbi, A Kalousis, A Kossenkov, A Sboner, AC Haury, AL Boulesteix, Arkady B. Khodursky, B Di Camillo, B Efron, B Efron, B Efron, B Schowe, C Cortes, C Cortes, C Furlanello, C Schneider, C Schneider, C Soneson, C Yao, Cesare Furlanello, Consortium The MicroArray Quality Control (MAQC), D Albanese, D Cai, D Corrada, D Critchlow, D Saari, D Witten, G Guzzetta, G Jurman, G Jurman, G Lance, G Lance, G Smyth, Giuseppe Jurman, GS Cheon, I Guyon, I Jeffery, I Lönnstedt, J Bar-Ilan, J Borda, J Chen, J Ioannidis, J Neter, J Storey, L Ein-Dor, L Kuncheva, L Yu, L Zhang, M Desarkar, M Kauers, M Kauers, M Kendall, M Schimek, M Schimek, M Slawski, M Villarino, M Villarino, O Bousquet, P Baldi, P Diaconis, P Diaconis, P Hall, P Hall, P Krízek, PC Boutros, R Fagin, R Gentleman, R Graham, R Pearson, R Pique-Regi, R Pique-Regi, R Simon, Roberto Visintainer, S Abramov, S Dudoit, S Lin, S Lin, S Mukherjee, S Setlur, S Simićc, S Vanderlooy, Samantha Riccadonna, SK Lau, T Bø, T Calders, V Tusher, Visintainer, W Fury, W Hoeffding, W Shi, X Wang, X Yang, Y Xiao, Y Xiao, Z He   +94 more
core   +4 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

A streamlined platform for analyzing tera-scale DDA and DIA mass spectrometry data enables highly sensitive immunopeptidomics

Nature Communications, 2022
Immunopeptidomics benefits from highly sensitive mass spectrometry (MS). Here, the authors present a computational platform for integrating data-dependent and -independent acquisition MS approaches, and demonstrate its utility for deeper immunopeptidome ...
Lei Xin, Rui Qiao, Xin Chen, Hieu Tran, Shengying Pan, Sahar Rabinoviz, Haibo Bian, Xianliang He, Brenton Morse, Baozhen Shan, Ming Li   +10 more
doaj   +1 more source

Development of Integrative Bioinformatics Applications using Cloud Computing resources and Knowledge Organization Systems (KOS). [PDF]

, 2005
Use of semantic web abstractions, in particular of domain neural Knowledge Organization Systems (KOS), to manage distributed, cloud based, integrative bioinformatics infrastructure.
Jonas Almeida, Jonas Almeida, Helena Deus, Wolfgang Maass   +3 more
core   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Ontologies for Bioinformatics

Bioinformatics and Biology Insights, 2008
The past twenty years have witnessed an explosion of biological data in diverse database formats governed by heterogeneous infrastructures. Not only are semantics (attribute terms) different in meaning across databases, but their organization varies ...
Nadine Schuurman, Agnieszka Leszczynski
doaj   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Dataset Lifecycle Framework and its applications in Bioinformatics [PDF]

, 2021
Yiannis Gkoufas, David Yu Yuan
openalex   +1 more source

Bioinformatics software, shifting to mobility [PDF]

, 2014
Presentación en Escuela de Verano del trabajo en desarrollo para el proyecto Mr.Symbiomath IAPP project (Code: 324554)Mobile devices are pervading all the work environments with such swiftness that makes past decades of computerization appear lethargic.
Falgueras-Cano, Juan
core  

Applications of next-generation sequencing technologies and computational tools in molecular evolution and aquatic animals conservation studies : a short review [PDF]

, 2019
Aquatic ecosystems that form major biodiversity hotspots are critically threatened due to environmental and anthropogenic stressors. We believe that, in this genomic era, computational methods can be applied to promote aquatic biodiversity conservation ...
Afiqah-Aleng, Nor, Danish-Daniel, Muhd, Mohd Nor, Siti Azizah, Razali, Siti Aisyah, Sorgeloos, Patrick, Sung, Yeong Yik, Tan, Min Pau, Van de Peer, Yves, Wong, Li Lian   +8 more
core   +1 more source