Results 51 to 60 of about 782,783 (305)

Introduction to Bioinformatics

, 2019
How the scientific community looks at molecular biology today is very different from that 50 years ago. During this time technological developments have led to many significant findings that have shook one of the most important foundations of molecular biology: the central dogma.
AYYILDIZ, DILARA, Piazza S.
openaire   +3 more sources

Structural and energetic basis of marine phytochemicals as dengue NS1 protein inhibitors

Scientific Reports
Dengue, spread by Aedes aegypti and Aedes albopictus, causes 390 million infections, 50 million illnesses, and 24,000 fatalities, including over 4.5 million in 2023.
Sanjida Mahjabin Sanju, Md. Meherajul Kabir, Md. Ifteker Hossain, Ahamad Arafat Rizbi, Mehajabin Nusrat Nadia, Jannatul Ferdous, Mst. Ruma Akter, Nazia Kamal, Farhana Mansoor Priya, Noimul Hasan Siddiquee   +9 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Design of a global population-covering multi-epitope mRNA vaccine against Lassa virus using immunoinformatics

Scientific Reports
The Lassa virus (LV) is a hemorrhagic virus that causes Lassa fever (LF). Despite its high mortality rate in Africa, no FDA-approved mRNA vaccine currently exists.
Noimul Hasan Siddiquee, Md Shoyaib Hossan Sami, Md. Aftabur Rahman, Md. Al-Amin, Md. Al-Amin Biswash, Kangkan Sharma, Kutub Uddin Samrat, Md. Ifteker Hossain, Ahmad Abdullah Mahdeen   +8 more
doaj   +1 more source

Reproducible bioinformatics project: a community for reproducible bioinformatics analysis pipelines

BMC Bioinformatics, 2018
Background Reproducibility of a research is a key element in the modern science and it is mandatory for any industrial application. It represents the ability of replicating an experiment independently by the location and the operator.
Neha Kulkarni, Luca Alessandrì, Riccardo Panero, Maddalena Arigoni, Martina Olivero, Giulio Ferrero, Francesca Cordero, Marco Beccuti, Raffaele A. Calogero   +8 more
doaj   +1 more source

Bi-directional gene set enrichment and canonical correlation analysis identify key diet-sensitive pathways and biomarkers of metabolic syndrome.

, 2010
peer-reviewedBackground Currently, a number of bioinformatics methods are available to generate appropriate lists of genes from a microarray experiment.
Morine Melissa J, Aidan P Moloney, Toomey Sinead, Melissa J Morine, McMonagle, Jolene, Roche, Helen M., Gaora Peadar Ó, Moloney, Aidan P, Isobel C Gormley, Helen M Roche, O Gaora, Peadar, Peadar Ó Gaora, Roche Helen M, Moloney Aidan P, Reynolds Clare M, Sinead Toomey, Toomey, Sinead, Jolene McMonagle, Clare M Reynolds, Morine, Melissa J, McMonagle Jolene, Gormley, Isobel C, Gormley Isobel C, Reynolds, Clare M   +23 more
core   +1 more source

developing-bioinformatics/bioinformatics: Introduction to Bioinformatics FA2019 v1.0

, 2020
<p>Course notes and code for BIO331 Introduction to Bioinformatics FA2019 at Stonehill College.</p ...
Rob Harbert
core   +1 more source

A quantitative account of genomic island acquisitions in prokaryotes [PDF]

, 2011
Background Microbial genomes do not merely evolve through the slow accumulation of mutations, but also, and often more dramatically, by taking up new DNA in a process called horizontal gene transfer.
van Passel, Mark W. J., van Passel Mark WJ, Passel, M.W.J., van, Mark WJ van Passel, Roos Tom E, Roos, T.E., van Passel, M.W.J., Roos, Tom E., Tom E Roos   +8 more
core   +1 more source

The Helmholtz Network for Bioinformatics: an integrative web portal for bioinformatics resources

, 2022
S.268-270The Helmholtz Network for Bioinformatics (HNB) is a joint venture of eleven German bioinformatics research groups that offers convenient access to numerous bioinformatics resources through a single web portal.
Crass, T., Christensen, M., Claussen, H., Antes, I., Basekow, W., Bork, P., Buning, C., Gailus-Durner, V., Ernst, P., Ebeling, C.   +9 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source