Results 41 to 50 of about 1,289,019 (331)
BMC Genomics, 2017 Background Next-generation sequencing is widely used to identify disease-causing variants in patients with rare genetic disorders. Identifying those variants from whole-genome or exome data can be both scientifically challenging and time consuming.
Andreas Krämer +4 more
doaj +1 more source
Crowdsourcing for bioinformatics [PDF]
Bioinformatics, 2013 Abstract Motivation: Bioinformatics is faced with a variety of problems that require human involvement. Tasks like genome annotation, image analysis, knowledge-base population and protein structure determination all benefit from human input.
Good, Benjamin M., Su, Andrew I.
openaire +3 more sources
MACBenAbim: A Multi-platform Mobile Application for searching keyterms in Computational Biology and Bioinformatics [PDF]
, 2012 Computational biology and bioinformatics are gradually gaining grounds in Africa and other developing nations of the world. However, in these countries, some of the challenges of computational biology and bioinformatics education are inadequate ...
Adewumi, A. O. +2 more
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Briefings in BioinformaticsAbstract Bioinformatics has revolutionized biology and medicine by using computational methods to analyze and interpret biological data. Quantum mechanics has recently emerged as a promising tool for the analysis of biological systems, leading to the development of quantum bioinformatics.
Majid Mokhtari +4 more
openaire +2 more sources
Educating the educators: Incorporating bioinformatics into biological science education in Malaysia [PDF]
, 2012 Bioinformatics can be defined as a fusion of computational and biological sciences. The urgency to process and analyse the deluge of data created by proteomics and genomics studies has caused bioinformatics to gain prominence and importance. However, its
Hussein, Huszalina +3 more
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In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
PLoS Computational Biology, 2019 Bioinformatics has become an indispensable part of life science over the past 2 decades. However, bioinformatics education is not well integrated at the undergraduate level, especially in liberal arts colleges and regional universities in the United ...
Yingqian Ada Zhan +5 more
doaj +1 more source
Streamlined and on-demand preparation of mRNA products on a universal integrated platform
Microsystems & Nanoengineering, 2023 Vaccines are used to protect human beings from various diseases. mRNA vaccines simplify the development process and reduce the production cost of conventional vaccines, making it possible to respond rapidly to acute and severe diseases, such as ...
Hongjuan Wei +5 more
doaj +1 more source
GPU cards as a low cost solution for efficient and fast classification of high dimensional gene expression datasets [PDF]
, 2010 The days when bioinformatics tools will be so reliable to become a standard aid in routine clinical diagnostics are getting very close. However, it is important to remember that the more complex and advanced bioinformatics tools become, the more ...
Benso, Alfredo +4 more
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