Results 151 to 160 of about 1,093,449 (328)

Potential molecular target screening and bioinformatics analysis of cholangiocarcinoma based on GEO database

, 2022
Zhen Yu, Jing Wu, Lei Zhang, Shuye Liu
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Bioinformatic analysis of miRNA expression patterns in TFF2 knock-out mice

, 2014
Yi Yin, Hong‐Wei Shan, Wanjie Huang, Yapeng Wu, Huijuan Lu, Ying Jin   +5 more
openalex   +1 more source

Screening and bioinformatics analysis of thyroid cancer-related hub genes

, 2020
ShuFei Wu, Shuang Yang, Jiu Pu, ZhengHai Ling, ZhengWei Leng, LingMi Hou   +5 more
openalex   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Introducing evolutionary biologists to the analysis of big data: guidelines to organize extended bioinformatics training courses [PDF]

, 2018
Rui Faria, Deborah A. Triant, Álvaro Perdomo-Sabogal, Bert Overduin, Christoph Bleidorn, Clara Isabel Bermúdez-Santana, David Langenberger, Giovanni Marco Dall’Olio, Henrike Indrischek, Jan Aerts, Jan Engelhardt, Johannes Engelken, Katja Liebal, Mario Fasold, Sofia Robb, Sonja Grath, Sree Rohit Raj Kolora, Tiago Carvalho, Walter Salzburger, Vladimir Jovanović, Katja Nowick   +20 more
openalex   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Identification of Potential core genes in Sevoflurance induced Myocardial Energy Metabolism in Patients Undergoing Off-pump Coronary Artery Bypass Graft Surgery using Bioinformatics analysis [PDF]

, 2019
Hua Lin
openalex   +1 more source

Supplementary Tables S1-S4 from Clinical Validation of Colorectal Cancer Biomarkers Identified from Bioinformatics Analysis of Public Expression Data [PDF]

, 2023
Yeon‐Joo Jung, Sang‐Hyuk Lee, Hyung-Seok Choi, Soonnam Kim, Eun Young Lee, Youngah Shin, Jihae Seo, Bumjin Kim, Yeonhwa Jung, Wankyu Kim, Ho-Kyung Chun, Woo Yong Lee, Jaesang Kim   +12 more
openalex   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source