Results 21 to 30 of about 1,151,634 (240)

Sickle Cell Disease Is an Inherent Risk for Asthma in a Sibling Comparison Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Sickle cell disease (SCD) and asthma share a complex relationship. Although estimates vary, asthma prevalence in children with SCD is believed to be comparable to or higher than the general population. Determining whether SCD confers an increased risk for asthma remains challenging due to overlapping symptoms and the ...
Suhei C. Zuleta De Bernardis   +9 more
wiley   +1 more source

Addressing the needs of traumatic brain injury with clinical proteomics. [PDF]

open access: yes, 2014
BackgroundNeurotrauma or injuries to the central nervous system (CNS) are a serious public health problem worldwide. Approximately 75% of all traumatic brain injuries (TBIs) are concussions or other mild TBI (mTBI) forms.
Loo, Joseph A   +3 more
core   +1 more source

Pazopanib Combined With Vincristine and Irinotecan in Relapsed Wilms Tumor: Encouraging Outcomes in a Heavily Pretreated Pediatric Cohort

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background While Wilms tumor (WT) typically has a favorable prognosis, relapsed cases—especially those with high‐risk histology—remain therapeutically challenging after intensive frontline therapy. The combination of vincristine and irinotecan has demonstrated activity in pediatric solid tumors, and pazopanib, a multi‐targeted tyrosine kinase ...
Maria Debora De Pasquale   +6 more
wiley   +1 more source

The Potential Clinical and Economic Value of Primary Tumour Identification in Metastatic Cancer of Unknown Primary Tumour: A Population-Based Retrospective Matched Cohort Study. [PDF]

open access: yes, 2017
PurposeSeveral genomic tests have recently been developed to identify the primary tumour in cancer of unknown primary tumour (CUP). However, the value of identifying the primary tumour in clinical practice for CUP patients remains questionable and ...
Brackstone, Muriel   +8 more
core   +1 more source

Biological Measurements Using Polymer Particles Focussing on Clinical Diagnostic and Research Fields

open access: yesKobunshi, 2005
高分子微粒子は,ゲノム創薬,プロテオミクスなどの先端研究から実用的な臨床検査まで広く利用されており,バイオ・メディカル計測におけるキーマテリアルである。微量のサンプルから非常に低濃度の物質を計測するバイオ・メディカル計測では,タンパク質や核酸の非特異的な吸着の少ない材料表面の設計が計測感度の向上に重要である。
Mikio HIKATA, Mitsuhiro MURATA
openaire   +2 more sources

Potential Early Risk Biomarkers for Reduced Forced Expiratory Volume in Children Post‐Hematopoietic Cell Transplantation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT We sought to identify potential early risk biomarkers for lung disease in children post‐allogeneic HCT. Patients with pulmonary function tests 3 months post‐transplant and plasma samples between days 7 and 14 post‐HCT were included. Six of 27 subjects enrolled had reduced forced expiratory volume 1 (FEV1) z scores.
Isabella S. Small   +3 more
wiley   +1 more source

Biophotonic Tools in Cell and Tissue Diagnostics. [PDF]

open access: yes, 2007
In order to maintain the rapid advance of biophotonics in the U.S. and enhance our competitiveness worldwide, key measurement tools must be in place. As part of a wide-reaching effort to improve the U.S.
Brownstein, Michael   +8 more
core   +2 more sources

Diagnostic nanoparticle targeting of the EGF-receptor in complex biological conditions using single-domain antibodies

open access: yesNanoscale, 2014
Nanoparticles functionalized with single domain antibodies are shown to specifically target the EGF receptor in vitro. We investigate the effects on uptake and specificity when increasing the environmental serum toward more in vivo "realistic" concentrations.
K. Zarschler   +7 more
openaire   +4 more sources

Nutritional and Behavioral Intervention for Long‐Term Childhood Acute Leukemia Survivors With Metabolic Syndrome

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Metabolic syndrome (MetS) is a common complication in survivors of childhood acute lymphoblastic and myeloid leukemia (AL), and a major risk factor for premature cardiovascular disease, type‐2‐diabetes, and metabolic dysfunction‐associated steatotic liver disease (MASLD).
Visentin Sandrine   +10 more
wiley   +1 more source

The Empower project : a new way of assessing and monitoring test comparability and stability [PDF]

open access: yes, 2015
Background: Manufacturers and laboratories might benefit from using a modern integrated tool for quality management/assurance. The tool should not be confounded by commutability issues and focus on the intrinsic analytical quality and comparability of ...
De Grande, Linde   +4 more
core   +1 more source

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