Results 41 to 50 of about 10,798 (169)

Biological Effects of Low Dose Radiation from Computerized Tomography Scans [PDF]

open access: yes, 2010
Humans have evolved under a field of low level radiation, and continue to be exposed to ubiquitous levels from natural and man-made sources including diagnostic radiology.
Asis, Angelica
core  

Self-Explanation Use in Nurse Practitioner Student Diagnostic Reasoning

open access: yes, 2020
There is a major gap in educational best-practices regarding how to scholastically foster diagnostic accuracy among Nurse Practitioner (NP) students.
Leah Susanne Burt (10212014)
core   +1 more source

Somatic symptoms of generalized anxiety disorder from the DSM-IV: Associations with pathological worry and depression symptoms in a nonclinical sample [PDF]

open access: yes, 1999
The present study investigates specificity of the six somatic symptoms that are associated with generalized anxiety disorder (GAD), according to the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders.
Joormann, Jutta   +3 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Utility of novel diagnostic tests for tuberculosis using human urine

open access: yes, 2012
Includes abstract.Includes bibliographical references.Two thirds of new TB cases in sub-Saharan Africa are HIV coinfected. HIV-TB co-infection increases the incidence of extra-pulmonary, sputum smear-negative and sputum-scarce TB.
Muchinga, Tapuwa Enwell
core  

A Distinct Urinary Biomarker Pattern Characteristic of Female Fabry Patients That Mirrors Response to Enzyme Replacement Therapy [PDF]

open access: yes, 2011
Female patients affected by Fabry disease, an X-linked lysosomal storage disorder, exhibit a wide spectrum of symptoms, which renders diagnosis, and treatment decisions challenging.
Breunig Frank   +69 more
core   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Addiction Phenomenology In Substance Use And Non-Substance Use Disorders

open access: yes, 2008
There is growing research evidence and public concern over the burgeoning of disorders which share common features with substance addictions. In order to investigate the presence and role of addiction features in disorders outside of substance addictions,
McLachlan, Andre David
core  

Microarrays – new possibilities for detecting biological factors hazardous for humans and animals, and for use in environmental protection

open access: yes, 2015
Both the known biological agents that cause infectious diseases, as well as modified (ABF-Advanced Biological Factors) or new, emerging agents pose a significant diagnostic problem using previously applied methods, both classical, as well as based on ...
Janusz Kocik   +6 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

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