Results 91 to 100 of about 2,333,106 (317)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Promising Prodiginins Biological Activities

Chemistry & Biodiversity
ABSTRACTProdiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto, Melisa E. Gantner, Boris E. Rodenak‐Kladniew, Santiago Rodriguez, María L. Cuestas, Alan Talevi, Guillermo R. Castro   +6 more
openaire   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Synthesis, computational studies and In Silico approaches of novel organophosphorus derivatives as anti-Alzheimer Agents

Scientific African
A novel established of compounds as 1,2-oxaphosphol-3-ene 3 and tetraethyl 4-nitroalk-1-ene-2,3-diyldiphosphonate 4a-e were synthesized through the coupling reaction of phosphonoallyl bromide E-2 with triethyl ammonium formate (TEAF) and nitroalkane ...
Maha Ameur, Rania Omrani, Sonia Taktouk, Anis Raddaoui, Ahmed Ridha El Ouederni, Rafik Gatri   +5 more
doaj   +1 more source

Synthesis and Biological Activity of Novel (Z)- and (E)-Verbenone Oxime Esters [PDF]

, 2017
Qiong Hu, Guishan Lin, Wengui Duan, Min Huang, Fuhou Lei   +4 more
openalex   +1 more source

Scrophulariae Radix: An Overview of Its Biological Activities and Nutraceutical and Pharmaceutical Applications [PDF]

, 2021
Hae-Jin Lee, Hae Lim Kim, Dong-Ryung Lee, Bong‐Keun Choi, Seung Hwan Yang   +4 more
openalex   +1 more source

Biologically Active Oxidized Phospholipids [PDF]

Journal of Biological Chemistry, 1999
T M, McIntyre, G A, Zimmerman, S M, Prescott   +2 more
openaire   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Eco-friendly Synthesis, antibacterial evaluation and in-silico profiling of Thioamide derivatives as dual-action potential dual-action agents

Results in Chemistry
An efficient, solvent-free synthesis of novel phosphono fluoro thioamidate derivatives 1–5 was achieved by reacting isothiocyanate derivatives with bis(2,2,2-trifluoroethyl) phosphonate at room temperature.
Rania Omrani, Imen Kharmachi, Sonia Taktouk, Mohamed Amine Ben Abdallah, Anis Raddaoui, Azaiez Ben Akacha   +5 more
doaj   +1 more source

Chemical Composition and Biological Activities of the Nord-West Romanian Wild Bilberry (Vaccinium myrtillus L.) and Lingonberry (Vaccinium vitis-idaea L.) Leaves [PDF]

, 2020
Bianca Eugenia Ștefănescu, Lavinia Florina Călinoiu, Floricuța Ranga, Florinela Fetea, Andrei Mocan, Dan Cristian Vodnar, Gianina Crișan   +6 more
openalex   +1 more source