Results 181 to 190 of about 16,621,712 (406)

Relationship between the molecular composition, visible light absorption, and health-related properties of smoldering woodsmoke aerosols [PDF]

, 2019
Organic aerosols generated from the smoldering combustion of wood critically impact air quality and health for billions of people worldwide; yet, the links between the chemical components and the optical or biological effects of woodsmoke aerosol (WSA ...
Denison, MS, He, G, Kam Chan, L, Karim, N, Nguyen, KQ, Nguyen, TB, Rice, RH, Yang, Y   +7 more
core  

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Cognitive, social, and behavioral effects of music and motor intervention in children with autism spectrum disorder: the role of time of day

Frontiers in Pediatrics
This study aimed to determine the effect of 12 weeks of specific training (combining movement and music intervention) on children with autism spectrum disorders (ASD), specifically by comparing the time of day (morning vs.
Chayma Kanzari, Aymen Hawani, Aymen Hawani, Bassem Mkaouer, Bassem Mkaouer, Maher Mrayeh, Maher Mrayeh, Santo Marsigliante, Antonella Muscella   +8 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

3-methoxy-dihydrofluoran-6-OL-6-phosphate - A fluorogenic substrate for the detection of enzymatic activities [PDF]

Organic phosphate compound synthesis, purification and use in detection of enzymatic activity in soils by fluorescence after biological ...
Shneour, E. A.
core   +1 more source

Cladobotryum mycophilum as Potential Biocontrol Agent [PDF]

, 2019
A study was conducted to explore the efficacy of potential biocontrol agent Cladobotryum mycophilum against different phytopathogenic fungi. The growth rates of 24 isolates of C. mycophilum were determined, and their antagonistic activity was analysed in
Diánez Martínez, Fernando José, Gea, Francisco J., Moreno Gavira, Alejandro, Santos Hernández, Milagrosa, Sánchez Montesinos, Brenda   +4 more
core   +1 more source

Antiurease screening of alkyl chain-linked thiourea derivatives: in vitro biological activities, molecular docking, and dynamic simulations studies

, 2022
Sana Yaqoob, Abdul Hameed, Mahmood Ahmed, Muhammad Imran, Muhammad Abdul Qadir, Mahwish Ramzan, Numan Yousaf, Jamshed Iqbal, Muhammad Muddassar   +8 more
openalex   +2 more sources

Biological Activity of Selected Natural and Synthetic Terpenoid Lactones [PDF]

, 2021
Alicja K. Surowiak, Lucyna Balcerzak, Stanisław Lochyński, Daniel Jan Strub   +3 more
openalex   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source