Results 201 to 210 of about 16,187,582 (338)

Synthesis, computational studies and In Silico approaches of novel organophosphorus derivatives as anti-Alzheimer Agents

Scientific African
A novel established of compounds as 1,2-oxaphosphol-3-ene 3 and tetraethyl 4-nitroalk-1-ene-2,3-diyldiphosphonate 4a-e were synthesized through the coupling reaction of phosphonoallyl bromide E-2 with triethyl ammonium formate (TEAF) and nitroalkane ...
Maha Ameur, Rania Omrani, Sonia Taktouk, Anis Raddaoui, Ahmed Ridha El Ouederni, Rafik Gatri   +5 more
doaj  

Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?

Molecular Oncology, EarlyView.
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley   +1 more source

Multifaceted Biological Activity of Rutin, Quercetin, and Quercetin's Glucosides. [PDF]

Molecules
Zielińska D, Starowicz M, Wronkowska M, Zieliński H.   +3 more
europepmc   +1 more source

Studies on metabolism of vitamin A. 1. The biological activity of vitamin A acid in rats [PDF]

, 1963
P. Malathi, K. Subba Rao, PS Sastry, J. Ganguly   +3 more
openalex   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

Synthesis and biological activity study of tanshinone I-pyridinium salt derivatives. [PDF]

Nat Prod Bioprospect
Zhao H, Wang Y, Liu Z, Lin L, Xiang J, Zhu Z, Yang X, Fang Y, Kong L, Li Y.   +9 more
europepmc   +1 more source

Biological activities in Edmonton soil as influenced by crop sequences /

, 1932
Vladimir Ignatieff
openalex   +2 more sources

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Investigation on the Influence of Aerial-Earth Circuit on the Biological Activities

, 1933
Arao Itano
openalex   +2 more sources

Biological Activity of a Phytotoxic Glycopeptide Produced by Corynebacterium sepedonicum [PDF]

, 1968
Gary A. Strobel, W. M. Hess
openalex   +1 more source