Results 41 to 50 of about 16,621,712 (406)

Providing the basis for a patient-centred and effective screening for cancer-related fatigue (MERLIN study): design of a longitudinal observational study

open access: yesBMJ Open, 2023
Introduction Cancer-related fatigue (CRF) is a frequent and burdensome sequela of cancer and cancer therapies. It can persist from months to years and has a substantial impact on patients’ quality of life and functioning.
Martina E Schmidt   +5 more
doaj   +1 more source

A Mild Synthesis of New Aryl Vinyl Ethers and Diethyl 1-[(Alkyl)(cyano)methyl]vinylphosphonates via the Substitution of a 2,3-Difunctional Allyl Bromide

open access: yesThe Scientific World Journal, 2014
A novel class of aryl vinyl ethers 3 and diethyl 3-cyano-3-alkylprop-1-en-2-ylphosphonates 4 has been prepared, respectively, from coupling reaction of diethyl 1-(bromomethyl)-2-cyanovinylphosphonate 2 with phenols and Gilman reagents.
Asma Fray   +3 more
doaj   +1 more source

Derivatives of Isoindoline, Synthesis and Biological Activity. II. Biological Activity of Derivatives of Isoindoline [PDF]

open access: yesKemija u Industriji, 2014
The derivatives of isoindolines show different biological activity in vitro and in vivo and it is hopeful that some of the compounds of this group will develop into new efficient drugs for different types of diseases in the future.
Sović, I., Karminski-Zamola, G.
doaj   +1 more source

Synthetic chemistry and biological activity of pentafluorosulphanyl (SF5) organic molecules [PDF]

open access: yes, 2012
Acknowledgements We thank the European Commission for financial support (Industry Academia Partnerships and Pathways project “PET BRAIN”, Contract No 251482). S.A.
Altomonte, Stefano, Zanda, Matteo
core   +1 more source

Biological Activity of Berberine—A Summary Update

open access: yesToxins, 2020
Berberine is a plant metabolite belonging to the group of isoquinoline alkaloids with strong biological and pharmacological activity. Currently, berberine is receiving considerable interest due to its anticancer activity based on many biochemical ...
Anna Och, Rafał Podgórski, R. Nowak
semanticscholar   +1 more source

Review of the synthesis and biological activity of thiazoles

open access: yesSynthetic Communications, 2020
This study covers the literature documents available on the chemistry of preparation of thiazoles. Additionally, we cover the biological activities of certain thiazoles.
Sukinah H. Ali, A. R. Sayed
semanticscholar   +1 more source

BIOLOGICAL ACTIVITIES OF LEUPEPTINS

open access: yesThe Journal of Antibiotics, 1969
Leupeptins, leupeptin Pr and leupeptin Ac, strongly inhibit proteolysis by plasmin, trypsin and papain, but do not inhibit proteolysis by α-chymotrypsin. The inhibition is competitive with substrates. The inhibitory effect on esterolysis by plasmin and trypsin is weaker than on proteolysis.
TAKAAKI AOYAGI   +7 more
openaire   +3 more sources

Type 2 diabetes and obesity induce similar transcriptional reprogramming in human myocytes

open access: yesGenome Medicine, 2017
Background Skeletal muscle is one of the primary tissues involved in the development of type 2 diabetes (T2D). The close association between obesity and T2D makes it difficult to isolate specific effects attributed to the disease alone.
Leif Väremo   +7 more
doaj   +1 more source

Biological Activity of Ionic Liquids and Their Application in Pharmaceutics and Medicine.

open access: yesChemical Reviews, 2017
Ionic liquids are remarkable chemical compounds, which find applications in many areas of modern science. Because of their highly tunable nature and exceptional properties, ionic liquids have become essential players in the fields of synthesis and ...
K. S. Egorova, E. Gordeev, V. Ananikov
semanticscholar   +1 more source

Photoswitchable catalysis by a nanozyme mediated by a lightsensitive cofactor [PDF]

open access: yes, 2017
The activity of a gold nanoparticle-based catalyst can be reversibly up- and down-regulated by light. Light is used to switch a small molecule between cis- and trans-isomers, which inhibits the catalytic activity of the nanoparticles to different extent.
Martin, Sergio Garcia   +3 more
core   +2 more sources

Home - About - Disclaimer - Privacy