Results 111 to 120 of about 7,692,235 (287)

Prognostic Value of Neurofilament Light Chain and Glial Fibrillary Acidic Protein in ALD‐Related Myelopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak, Marije M. C. Voermans, Hans Heijst, Charlotte E. Teunissen, Marc Engelen   +4 more
wiley   +1 more source

Reduced central thyroid hormone sensitivity is associated with adverse body composition and lower biological age acceleration in euthyroid adults

European Journal of Medical Research
Background Central thyroid hormone sensitivity reflects the responsiveness of the hypothalamic-pituitary-thyroid feedback axis to circulating thyroid hormones.
Xin Zhao, Minne Sun, Yunlu Sheng, Jing Yu, Xiaona Li, Qun Zhang, Jianming Wang, Guoxian Ding   +7 more
doaj   +1 more source

Differential associations of dietary inflammatory potential, antioxidant capacity, and Mediterranean diet adherence with biological aging: A UK Biobank study

The Journal of Nutrition, Health and Aging
Background: Biological aging, distinct from chronological age, significantly impacts chronic disease risk and is a crucial target for health interventions.
Cong Zhang, Ren-Fang Han, Song Yin, Yue-Qing Huang   +3 more
doaj   +1 more source

Annual Report - Marine Biological Laboratory, 2002

, 2003
Annual report of the Marine Biological Laboratory in Woods Hole. 2002.
Marine Biological Laboratory (Woods Hole MA)
core  

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng, Diego Z. Carvalho, Shahid Karim, Anwar Chahal, Virend K. Somers   +4 more
wiley   +1 more source

Associations of Biological Age and Heart Age Accelerations With New‐Onset Stroke in Individuals With Cardiovascular‐Kidney‐Metabolic Syndrome Stages 0–3: Evidence From a Chinese Longitudinal Study

The Journal of Clinical Hypertension
Individuals with cardiovascular‐kidney‐metabolic (CKM) syndrome face an elevated risk of stroke, yet effective risk stratification indicators remain limited.
Hao Zhu, Hannah Lui, Li He, Jing Zhang, Zhi Jin   +4 more
doaj   +1 more source

Biological aging mediates and frailty modifies the associations of arterial stiffness with incident probable sarcopenia and sarcopenia: a prospective cohort study of UK biobank

Frontiers in Public Health
BackgroundArterial stiffness may contribute to sarcopenia, but whether biological aging mediates and frailty modifies these associations remains unclear.MethodsThis prospective cohort study included 32,451 UK Biobank participants free of probable ...
Aochuan Sun, Yike Du, Yike Du, Xusheng Yang, Hao Liu, Ruowei Zeng, Yang Wu, Yang Wu, Zhengtang Liu, Zhengtang Liu   +9 more
doaj   +1 more source

Annual Report - Marine Biological Laboratory, 1950

, 1951
Annual report of the Marine Biological Laboratory in Woods Hole. 1950.
Marine Biological Laboratory (Woods Hole MA)
core  

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Frequent Sweetened Beverage Consumption Is Associated With Accelerated Biological Aging: Evidence From a Population‐Based Study and Gut Microbiota Analysis

Advanced Science
Although substantial evidence links sweetened beverage (SB) intake to chronic diseases, its association with biological aging and underlying mechanisms remains unclear. This population‐based study included 9104 adults aged 18–80 years from the WELL‐China
Yuwei Shi, Xinmei Li, Yufan Hao, Qiaoyu Wu, Yuji Yu, Siyu Li, Nuo Xu, Yi‐Hsuan Wu, Eunhye Lee, Chi Chang, Emily Hu, Ying Lu, Elizabeth Delzell, Ann W. Hsing, Shankuan Zhu   +14 more
doaj   +1 more source