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Longitudinal biological aging trajectories and incident urolithiasis: a causal mediation analysis role of metabolic dysfunction in a large Chinese cohort [PDF]
Frontiers in EndocrinologyBackgroundBiological aging varies significantly between individuals, yet how its longitudinal dynamics influence urolithiasis risk remains poorly understood.
Jialong Wang +5 more
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Chronological and biological age: Why relevant for psychiatrists?
European Psychiatry, 2021 Introduction Depression is the mental disorder with the largest disease burden impact. That is due to its high prevalence, chronicty, early onset but also due to its impact on various aging-related somatic morbidities and mortality.
B. Penninx
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Frailty and Biological Age [PDF]
Annals of Geriatric Medicine and Research, 2021 A reliable model of biological age is instrumental in the field of geriatrics and gerontology. This model should account for the heterogeneity and plasticity of aging and also accurately predict aging-related adverse outcomes. Epigenetic age models are based on DNA methylation levels at selected genomic sites and can be significant predictors of ...
Lixin Ji +2 more
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Biological aging partly mediates the association between physical activity and overactive bladder: evidence from NHANES 2007-2020. [PDF]
Clin EpigeneticsHuang J +6 more
europepmc +2 more sources
An integrative study of five biological clocks in somatic and mental health
eLife, 2021 Biological clocks have been developed at different molecular levels and were found to be more advanced in the presence of somatic illness and mental disorders. However, it is unclear whether different biological clocks reflect similar aging processes and
Rick Jansen +6 more
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Disparities in Biological Aging and Brain Health: Insights from Diverse Midlife Adults [PDF]
Alzheimers DementTurney I +9 more
europepmc +4 more sources
Biological Age Predictors [PDF]
EBioMedicine, 2017 The search for reliable indicators of biological age, rather than chronological age, has been ongoing for over three decades, and until recently, largely without success. Advances in the fields of molecular biology have increased the variety of potential candidate biomarkers that may be considered as biological age predictors.
Jylhävä, Juulia +2 more
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Biology, 2023 Biological aging biomarkers, such as leukocyte telomere length (LTL) and epigenetic clocks, have been associated with the risk of cerebral small vessel disease (CSVD) in several observational studies.
Biying Lin, Yuzhu Mu, Zhongxiang Ding
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Scaling in a continuous time model for biological aging [PDF]
, 2000 In this paper we consider a generalization to the asexual version of the Penna model for biological aging, where we take a continuous time limit.
G. L. THOMAS +3 more
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Frontiers in Neuroscience, 2023 BackgroundAging is a significant risk factor for many neurodegenerative diseases and neurological tumors. Previous studies indicate that the frailty index, facial aging, telomere length (TL), and epigenetic aging clock acceleration are commonly used ...
Zhiyun Zhang +6 more
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