Results 11 to 20 of about 911,648 (354)

Sex differences in biological aging with a focus on human studies

eLife, 2021
Aging is a complex biological process characterized by hallmark features accumulating over the life course, shaping the individual's aging trajectory and subsequent disease risks.
Sara Hägg, Juulia Jylhävä
doaj   +1 more source

Non cell autonomous upregulation of CDKN2 transcription linked to progression of chronic hepatitis C disease [PDF]

, 2013
Chronic hepatitis C virus infection (C-HC) is associated with higher mortality arising from hepatic and extrahepatic disease. This may be due to accelerated biological aging; however, studies in C-HC have thus far been based solely on telomere length as ...
Barclay, Stephen, McGuinness, Dagmara, McLauchlan, John, Mills, Peter R., Patel, Arvind H., Robinson, Mark W., Shiels, Paul G., Swann, Rachael   +7 more
core   +2 more sources

Historical and Heritage Sustainability for the Revival of Ancient Wine-Making Techniques and Wine Styles

Beverages, 2022
The purpose of this review is to provide a general description of ancient winemaking techniques and wine styles that were most lauded in antiquity, in support of their revival and dissemination today.
Mkrtich Harutyunyan, Manuel Malfeito-Ferreira   +1 more
doaj   +1 more source

Effects of aging on biological motion discrimination [PDF]

, 2009
Peer ...
Allison B. Sekuler, Alvarez, Andersen, Andersen, Andersen, Andersen, Atchley, Beintema, Bennett, Bennett, Bertenthal, Billino, Blake, Boutet, Brainard, Crum, Cutting, Cutting, Cutting, Del Viva, Dittrich, Fiorentini, Folstein, Gaspar, Gaspar, Giese, Gilmore, Grossman, Grossman, Grossman, Habak, Hua, Husk, Hussain, Johansson, Karin S. Pilz, Kessels, Kline, Kozlowski, Leventhal, Liang, Mather, Maurer, McLeod, Norman, Norman, Norman, Norman, Norman, Norman, Patrick J. Bennett, Pavlova, Pelli, Plude, Plude, Rabbitt, Richards, Roether, Roudaia, Roudaia, Salthouse, Salthouse, Saunders, Schmolesky, Sekuler, Sekuler, Sekuler, Snowden, Sumi, Tanaka, Thornton, Thornton, Trick, Troje, Vaina, Vanrie, Wist, Yang, Yang, Yu   +79 more
core   +1 more source

Spinal Cord Cells from Pre-metamorphic Stages Differentiate into Neurons and Promote Axon Growth and Regeneration after Transplantation into the Injured Spinal Cord of Non-regenerative Xenopus laevis Froglets

Frontiers in Cellular Neuroscience, 2017
Mammals are unable to regenerate its spinal cord after a lesion, meanwhile, anuran amphibians are capable of spinal cord regeneration only as larvae, and during metamorphosis, this capability is lost.
Emilio E. Méndez-Olivos, Rosana Muñoz, Juan Larraín   +2 more
doaj   +1 more source

Impact of genetic background and experimental reproducibility on identifying chemical compounds with robust longevity effects

Nature Communications, 2017
Irreproducibility of biological findings is a major challenge for drug development. Here the authors examine the lifespans of 22 worm strains in three different laboratories and the effects of ten known chemicals to assess reproducibility in the face of ...
Mark Lucanic, W. Todd Plummer, Esteban Chen, Jailynn Harke, Anna C. Foulger, Brian Onken, Anna L. Coleman-Hulbert, Kathleen J. Dumas, Suzhen Guo, Erik Johnson, Dipa Bhaumik, Jian Xue, Anna B. Crist, Michael P. Presley, Girish Harinath, Christine A. Sedore, Manish Chamoli, Shaunak Kamat, Michelle K. Chen, Suzanne Angeli, Christina Chang, John H. Willis, Daniel Edgar, Mary Anne Royal, Elizabeth A. Chao, Shobhna Patel, Theo Garrett, Carolina Ibanez-Ventoso, June Hope, Jason L Kish, Max Guo, Gordon J. Lithgow, Monica Driscoll, Patrick C. Phillips   +33 more
doaj   +1 more source

Aging Scaled Brownian Motion [PDF]

, 2015
Scaled Brownian motion (SBM) is widely used to model anomalous diffusion of passive tracers in complex and biological systems. It is a highly non-stationary process governed by the Langevin equation for Brownian motion, however, with a power-law time ...
Chechkin, A. V., Jafari, G. R., Metzler, R., Safdari, H.   +3 more
core   +3 more sources

Biological mechanisms of ageing [PDF]

Eye, 1987
In a short review of the theories or proposed biological mechanisms of ageing it is necessary to be very selective in the ideas which are included or rejected. Although many theories of ageing are advanced in the literature a high proportion can be considered to be special cases of a previous hypothesis. No one individual theory satisfactorily explains
openaire   +2 more sources

The Psychobiology of Bereavement and Health: A Conceptual Review From the Perspective of Social Signal Transduction Theory of Depression

Frontiers in Psychiatry, 2020
Losing a spouse is considered one of the most stressful life events a person can experience. Particularly in the immediate weeks and months after the loss, bereavement is associated with a significantly increased risk of morbidity and mortality.
Annina Seiler, Roland von Känel, George M. Slavich   +2 more
doaj   +1 more source

First passage statistics for aging diffusion in annealed and quenched disorder [PDF]

, 2014
Aging, the dependence of the dynamics of a physical process on the time $t_a$ since its original preparation, is observed in systems ranging from the motion of charge carriers in amorphous semiconductors over the blinking dynamics of quantum dots to the ...
Godec, Aljaz, Kruesemann, Henning, Metzler, Ralf   +2 more
core   +3 more sources