Results 41 to 50 of about 3,406,662 (333)
Background The World Health Organization proposed the concept of intrinsic capacity (IC; the composite of all the physical and mental capacities of the individual) as central for healthy ageing.
Robinson Ramírez‐Vélez +6 more
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Accelerated telomere attrition is associated with relative household income, diet and inflammation in the pSoBid cohort [PDF]
BACKGROUND: It has previously been hypothesized that lower socio-economic status can accelerate biological ageing, and predispose to early onset of disease.
Batty, G.D. +110 more
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Ageing is a diverse and multifaceted experience that is unique to each person. The process of ageing is lived differently according to each individual’s socio-cultural, historical, religious, and political context, among other factors.
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Individual differences in cognitive performance increase with advancing age, reflecting marked cognitive changes in some individuals along with little or no change in others. Genetic and lifestyle factors are assumed to influence cognitive performance in
Carl-Johan Boraxbekk +51 more
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Successful ageing in an area of deprivation: Part 1—A qualitative exploration of the role of life experiences in good health in old age [PDF]
Objectives: To determine the life histories and current circumstances of healthy and unhealthy older people who share an ecology marked by relative deprivation and generally poor health.
Cullen, B. +5 more
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Untargeted metabolomics for uncovering biological markers of human skeletal muscle ageing
Ageing compromises skeletal muscle mass and function through poorly defined molecular aetiology. Here we have used untargeted metabolomics using UHPLC-MS to profile muscle tissue from young (n=10, 25±4y), middle aged (n=18, 50±4y) and older (n=18, 70±3y)
Williams, John P +15 more
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A potential new biological marker of the biological age [PDF]
For many years, data have been accumulated which point to a significant similarity between the nature of the brain damage in the aging process (in the case of dementia or even in outwardly healthy elderly people) and the brain damage caused by prion diseases of humans and animals (Sobel, 1970; Fraser and McBride, 1985; Masters et al., 1985; Gajdusek ...
Zuev, Victor A. +2 more
openaire +3 more sources
Chemotherapy-induced acceleration of DNA methylation-based biological age in breast cancer
Breast cancer is the most common cancer diagnosed in women and is often treated with chemotherapy. Although previous studies have demonstrated increasing biological age in patients who receive chemotherapy, evaluation of this association with DNA ...
Drew R. Nannini +3 more
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The long lives of primates and the ‘invariant rate of ageing’ hypothesis
The ‘invariant rate of ageing’ hypothesis suggests that the rate of ageing tends to be constant within species. Here, Colchero et al. find support for the hypothesis across primates, including humans, suggesting biological constraints on the rate of ...
Fernando Colchero +39 more
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Eternal youth: a scientific approach to ageing [PDF]
The purpose of the study is to determine the causes of ageing and the ways to overcome it. Research objectives: ageing processes in the human body.
Maslakov, A. A.
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