Results 91 to 100 of about 6,324,191 (295)
Iterative focused screening with biological fingerprints identifies selective Asc-1 inhibitors distinct from traditional high throughput screening [PDF]
N-methyl-d-aspartate receptors (NMDARs) mediate glutamatergic signaling that is critical to cognitive processes in the central nervous system, and NMDAR hypofunction is thought to contribute to cognitive impairment observed in both schizophrenia and ...
Amoss, Adam+18 more
core +2 more sources
Biological Assay of Thyroprotein
Summary A new method for the biological assay of thyroidal substances based upon the determination of the thyroxine secretion rate (TSR) of rats is suggested. The mean TSR of a group of rats is first determined by thyroxine replacement. Thyroprotein is then injected subcutaneously in amount sufficient to block thyroidal-I 131 release in the ...
T.R. Bauman, C. W. Turner
openaire +2 more sources
Biological assay of glucagon in rabbits [PDF]
Bioassay of glucagon based on the hyper-glycaemic activity was investigated in normal rabbits. — It was shown that the index of precision (λ) derived from the dose response curve is about 1.2, which means that several hundred animals are required per assay in order to obtain a reasonably narrow confidence interval. Triple cross-over design improved the
B. Keiser-Nielsen+3 more
openaire +3 more sources
Cultivar de soja BR 36 com atividades de inibidores de tripsina convencional e linhagem BRM 95-5262, geneticamente modificadas para conter baixas atividades de inibidores de tripsina, contendo 40 e 20 e 30 e 20% de atividades residuais relativa de ...
Edna Mayumi Yuahasi Miura+4 more
doaj
Background/Objectives: Congenital heart disease (CHD) occurs in ~1% of all live neonates globally, rendering it the most prevalent developmental anomaly affecting humans; this condition confers substantial infant morbidity and mortality worldwide ...
Zi Yan+7 more
doaj +1 more source
A wash-free, dip-type fiber optic plasmonic (DiP) assay for sub-zeptomole analyte detection [PDF]
This study demonstrates a rapid, wash-free dip-type fiber optic plasmonic sandwich (DiP) assay capable of zeptomole analyte detection and 6-orders of wide dynamic range. The DiP assay is realized on a compact U-bent fiber optic probe surface by dipping the antibody functionalized probe into a mixture of sample solution and AuNP labeled reagent.
arxiv
Optimal Decision Theory for Diagnostic Testing: Minimizing Indeterminate Classes with Applications to Saliva-Based SARS-CoV-2 Antibody Assays [PDF]
In diagnostic testing, establishing an indeterminate class is an effective way to identify samples that cannot be accurately classified. However, such approaches also make testing less efficient and must be balanced against overall assay performance.
arxiv
RESUMO O objetivo do trabalho foi avaliar a resistência natural da madeira de carvoeiro (Sclerolobium paniculatum Vogel) a cupins xilófagos em ensaio de alimentação forçada.
Patricia Hellenn Stallbaun+5 more
doaj +1 more source
Changes in T cell effector functions over an 8-year period with TNF antagonists in patients with chronic inflammatory rheumatic diseases [PDF]
The aim of the study was to clarify the effect of long-term anti-TNF therapy on T cell function in patients with rheumatologic immune-mediated inflammatory diseases (IMID).
Mastroianni, Claudio Maria+6 more
core +1 more source
Isotachophoresis applied to chemical reactions [PDF]
This review discusses research developments and applications of isotachophoresis (ITP) to the initiation, control, and acceleration of chemical reactions, emphasizing reactions involving biomolecular reactants such as nucleic acids, proteins, and live cells.
arxiv