Results 71 to 80 of about 4,550,163 (310)

Annual Report - Marine Biological Laboratory, 1934

, 1935
Annual report of the Marine Biological Laboratory in Woods Hole. 1934.
Marine Biological Laboratory (Woods Hole MA)
core  

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Validation of an Analytical Procedure for Evaluating the Biological Activity of a Medicinal Product Based on Tocilizumab and Determination of Acceptance Criteria for Test Results

Регуляторные исследования и экспертиза лекарственных средств
INTRODUCTION. Bioanalytical techniques are characterised by greater variability and lower stability than physicochemical methods because live test systems are inherently labile.
Yu. A. Nikonova, S. G. Abbasova, P. E. Kargopolova, O. M. Strizhakova, I. V. Lyagoskin, A. P. Vasilev, A. S. Pershin   +6 more
doaj   +1 more source

Annual Report - Marine Biological Laboratory, 1929

, 1930
Annual report of the Marine Biological Laboratory in Woods Hole. 1929.
Marine Biological Laboratory (Woods Hole MA)
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Resistência Natural da Madeira de Sclerolobium paniculatum Vogel a Cupins em Condições de Laboratório

Floresta e Ambiente
RESUMO O objetivo do trabalho foi avaliar a resistência natural da madeira de carvoeiro (Sclerolobium paniculatum Vogel) a cupins xilófagos em ensaio de alimentação forçada.
Patricia Hellenn Stallbaun, Edy Eime Pereira Barauna, Juarez Benigno Paes, Nadrielle Charles Ribeiro, Thiago Campos Monteiro, Marina Donária Chaves Arantes   +5 more
doaj   +1 more source

Fabrication and In Vitro Biological Assay of Thermo-Mechanically Tuned Chitosan Reinforced Polyurethane Composites. [PDF]

Molecules, 2023
Akram N, Shahzadi I, Zia KM, Saeed M, Ali A, Al-Salahi R, Abuelizz HA, Verpoort F.   +7 more
europepmc   +1 more source

Annual Report - Marine Biological Laboratory, 1989

, 1990
Annual report of the Marine Biological Laboratory in Woods Hole. 1989.
Marine Biological Laboratory (Woods Hole MA)
core  

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Biological Assay to Determine Gonadotropin Potency: From In Vivo to In Vitro Sustainable Method. [PDF]

Int J Mol Sci, 2023
Nevelli F, Palmese A, Gleixner R, Peroglio F, D'Acunto CW, Dadone A, D'Hooghe T, Lispi M.   +7 more
europepmc   +1 more source