Results 51 to 60 of about 4,740,594 (312)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Durabilidade natural de espécies florestais madeireiras ao ataque de cupim de madeira seca

open access: yesFloresta e Ambiente
Esta pesquisa objetivou avaliar a resistência de dez madeiras ao térmita, Cryptotermes brevis, em condições de laboratório. As espécies estudadas foram amoreira (Chlorophora tinctoria), angelim-pedra (Hymenolobium petraeum), angico-vermelho ...
Fabricio Gomes Gonçalves   +4 more
doaj   +1 more source

A biobarcode assay incorporated microdevice for highly sensitive and multiplex biological agent detection

open access: yes, 2014
Early detection of biological agents is an important issue to prevent widespread damages in bioterrorism. Biobarcode assay would be an ideal platform for rapid, sensitive, and multiplex analysis of biological agents, and its combination with lab-on-a ...
Chung, Soyi   +4 more
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 1893

open access: yes, 1894
Annual report of the Marine Biological Laboratory in Woods Hole. 1893.
Marine Biological Laboratory (Woods Hole MA)
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

A colorimetric bioassay for quantitation of both basal and insulin-induced glucose consumption in 3T3-L1 adipose cells

open access: yesHeliyon, 2020
Introduction: The quantitation of glucose consumption in animal cell cultures is mainly based on the use of radiolabeled or fluorescent analogues, resulting in expensive and tedious procedures, requiring special equipment and, sometimes, with potential ...
Paola A. Rivera Diaz   +3 more
doaj   +1 more source

Annual Report - Marine Biological Laboratory, 1980

open access: yes, 1981
Annual report of the Marine Biological Laboratory in Woods Hole. 1980.
Marine Biological Laboratory (Woods Hole MA)
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

HPTLC assay of nicotine and cotinine in biological samples

open access: yesJournal of Mind and Medical Sciences, 2018
This study presents the development of a simple high-performance thin layer chromatography (HPTLC) method for the determination of nicotine and its metabolite cotinine in human plasma and urine. The following mobile phases: methanol: ammonia (100:1.5, v:
Ana Maria Vlasceanu   +6 more
doaj   +1 more source

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