Results 121 to 130 of about 4,550,163 (310)
Annual Report - Marine Biological Laboratory, 1892
Annual report of the Marine Biological Laboratory in Woods Hole. 1892.
Marine Biological Laboratory (Woods Hole MA)
core
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1983
Annual report of the Marine Biological Laboratory in Woods Hole. 1983.
Marine Biological Laboratory (Woods Hole MA)
core
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Validation of the micronucleus-centromere assay for biological dosimetry
The micronucleus assay is frequently used for purposes of biological dosimetry. Due to high interindividual variability in the spontaneous frequency of micronuclei, its sensitivity in the low dose region is poor.
Wojcik A. +6 more
doaj
Annual Report - Marine Biological Laboratory, 1894
Annual report of the Marine Biological Laboratory in Woods Hole. 1894.
Marine Biological Laboratory (Woods Hole MA)
core
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Assay of Properdin in Biological Fluids.
Summary1. A sensitive, reproducible assay for properdin is described using spectro-photometric determinations of C'3 content. 2. RP and R3 reagent sera for the properdin assay may be readily prepared from guinea pig serum. 3. RP and R3 from both human and guinea pig sources may be used interchangeably in the reported properdin assay. 4.
openaire +2 more sources
Annual Report - Marine Biological Laboratory, 1988
Annual report of the Marine Biological Laboratory in Woods Hole. 1988.
Marine Biological Laboratory (Woods Hole MA)
core
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source

