Results 131 to 140 of about 4,550,163 (310)

Annual Report - Marine Biological Laboratory, 1935

open access: yes, 1936
Annual report of the Marine Biological Laboratory in Woods Hole. 1935.
Marine Biological Laboratory (Woods Hole MA)
core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Iron bioavailability of different maize genotypes developed in a breeding program: in vitro and in vivo studies

open access: yesArchivos Latinoamericanos de Nutrición
The objective of this study was to evaluate iron bioavailability of maize genotypes, and analyze the correlation between in vitro and in vivo methods. Dialysable iron was analyzed in 13 genotypes from which 5 were selected for the biological assay.
Vânia Mayumi Nakajima   +5 more
doaj  

A Cost-Effective and Robust Cell-Based Bioassay Method for Evaluating the Bioactivity of Trastuzumab-like Antibodies

open access: yesBiomedicines
Background/Objectives: Trastuzumab is an effective therapeutic intervention for treating HER2-positive breast cancers. The cost-effectiveness, global demand, and patent expiration of trastuzumab have led to the inflow of its biosimilars in the global ...
Pooja Bharali   +2 more
doaj   +1 more source

Annual Report - Marine Biological Laboratory, 1943

open access: yes, 1944
Annual report of the Marine Biological Laboratory in Woods Hole. 1943.
Marine Biological Laboratory (Woods Hole MA)
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 1942

open access: yes, 1943
Annual report of the Marine Biological Laboratory in Woods Hole. 1942.
Marine Biological Laboratory (Woods Hole MA)
core  

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Expanded Tox21 Biological Assay Panel for the Prediction of Drug-Induced Liver Injury and Cardiotoxicity. [PDF]

open access: yesEnviron Health Perspect
Xu T   +17 more
europepmc   +2 more sources

Properties of Camphorated Paramonochlorophenol and Camphorated Paramonochlorophenol Associated to Calcium Hydroxide

open access: yesPesquisa Brasileira em Odontopediatria e Clínica Integrada, 2007
Objective: To evaluate the biocompatibility of camphoratedparamonochlorophenol (CMCP) at a proportion of 3.5:6.5 andcamphorate paramonochlorophenol associated to calcium hydroxide(CMCP+Ca(OH)2) in rat subcutaneous tissue, and the antimicrobialpotential ...
Halim NAGEM FILHO   +4 more
doaj  

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