Results 161 to 170 of about 4,740,594 (312)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
The application of single cell gel electrophoresis or comet assay to human monitoring studies
Salud Pública de México, 1999 Objective. In the search of new human genotoxic biomarkers, the single cell gel electrophoresis assay has been proposed as a sensible alternative. Material and methods.
Valverde Mahara +7 more
doaj
Reporting biological assay screening results for maximum impact. [PDF]
Drug Discov Today Technol, 2015 Bolton E.
europepmc +1 more source
Annual Report - Marine Biological Laboratory, 1921
, 1921 Annual report of the Marine Biological Laboratory in Woods Hole. 1921.
Marine Biological Laboratory (Woods Hole MA)
core
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Herpes murine model as a biological assay to test dialyzable leukocyte extracts activity. [PDF]
J Immunol Res, 2015 Salinas-Jazmín N +8 more
europepmc +1 more source
Annual Report - Marine Biological Laboratory, 1924
, 1924 Annual report of the Marine Biological Laboratory in Woods Hole. 1924.
Marine Biological Laboratory (Woods Hole MA)
core
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1918
, 1919 Annual report of the Marine Biological Laboratory in Woods Hole. 1918.
Marine Biological Laboratory (Woods Hole MA)
core
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source