Results 161 to 170 of about 4,550,163 (310)

Annual Report - Marine Biological Laboratory, 1924

, 1924
Annual report of the Marine Biological Laboratory in Woods Hole. 1924.
Marine Biological Laboratory (Woods Hole MA)
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

The application of single cell gel electrophoresis or comet assay to human monitoring studies

Salud Pública de México, 1999
Objective. In the search of new human genotoxic biomarkers, the single cell gel electrophoresis assay has been proposed as a sensible alternative. Material and methods.
Valverde Mahara, Ostrosky-Wegman Patricia, Rojas Emilio, Fortoul Teresa, Meneses Fernando, Ramírez Matiana, Díaz-Barriga Fernando, Cebrian Mariano   +7 more
doaj  

Reporting biological assay screening results for maximum impact. [PDF]

Drug Discov Today Technol, 2015
Bolton E.
europepmc   +1 more source

Annual Report - Marine Biological Laboratory, 1957

, 1957
Annual report of the Marine Biological Laboratory in Woods Hole. 1957.
Marine Biological Laboratory (Woods Hole MA)
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Herpes murine model as a biological assay to test dialyzable leukocyte extracts activity. [PDF]

J Immunol Res, 2015
Salinas-Jazmín N, Estrada-Parra S, Becerril-García MA, Limón-Flores AY, Vázquez-Leyva S, Medina-Rivero E, Pavón L, Velasco-Velázquez MA, Pérez-Tapia SM.   +8 more
europepmc   +1 more source

Annual Report - Marine Biological Laboratory, 1896-1902

, 1902
Annual report of the Marine Biological Laboratory in Woods Hole for the years 1896-1899.
Marine Biological Laboratory (Woods Hole MA)
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 1967

, 1968
Annual report of the Marine Biological Laboratory in Woods Hole. 1967.
Marine Biological Laboratory (Woods Hole MA)
core