Results 171 to 180 of about 4,550,163 (310)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Discovery of Novel Ligands for TNF-α and TNF Receptor-1 through Structure-Based Virtual Screening and Biological Assay. [PDF]
J Chem Inf Model, 2017 Chen S +7 more
europepmc +1 more source
Annual Report - Marine Biological Laboratory, 1926
, 1927 Annual report of the Marine Biological Laboratory in Woods Hole. 1926.
Marine Biological Laboratory (Woods Hole MA)
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1948
, 1948 Annual report of the Marine Biological Laboratory in Woods Hole. 1948.
Marine Biological Laboratory (Woods Hole MA)
core
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1952
, 1952 Annual report of the Marine Biological Laboratory in Woods Hole. 1952.
Marine Biological Laboratory (Woods Hole MA)
core
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Identification and characterization of loop7 motif and its role in regulating biological function of human APOBEC3G through molecular modeling and biological assay. [PDF]
Acta Pharm Sin B, 2017 Zhai C +10 more
europepmc +1 more source
Annual Report - Marine Biological Laboratory, 1936
, 1937 Annual report of the Marine Biological Laboratory in Woods Hole. 1936.
Marine Biological Laboratory (Woods Hole MA)
core