Results 171 to 180 of about 2,148,890 (355)

A novel medium-throughput biological assay system for HTLV-1 infectivity and drug discovery. [PDF]

Iran J Basic Med Sci, 2017
Abdizadeh MF, Makvandi M, Samarbafzadeh A, Azadmanesh K, Azadmanesh K.   +4 more
europepmc   +1 more source

CC-1065 (NSC-298223), a new antitumor antibiotic. Production, in vitro biological activity, microbiological assays and taxonomy of the producing microorganism.

, 1978
L. J. Haňka, A Dietz, S. A. Gerpheide, Sandra L. Kuentzel, David G. Martin   +4 more
openalex   +2 more sources

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Reporting biological assay screening results for maximum impact. [PDF]

Drug Discov Today Technol, 2015
Bolton E.
europepmc   +1 more source

Ultraperformance Liquid Chromatography Tandem Mass Spectrometry Assay of DNA Cytosine Methylation Excretion from Biological Systems [PDF]

Jing Qu, Avinash Kumar, Yi‐Ming Liu, Oluwatoyin V. Odubanjo, Felicite K. Noubissi, Yixin Hu, Hankun Hu   +6 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

The application of single cell gel electrophoresis or comet assay to human monitoring studies

Salud Pública de México, 1999
Objective. In the search of new human genotoxic biomarkers, the single cell gel electrophoresis assay has been proposed as a sensible alternative. Material and methods.
Valverde Mahara, Ostrosky-Wegman Patricia, Rojas Emilio, Fortoul Teresa, Meneses Fernando, Ramírez Matiana, Díaz-Barriga Fernando, Cebrian Mariano   +7 more
doaj  

Mechanism of nitrosothiol formation in biological systems: Analysis by an HPLC/flow reactor assay

, 1998
Takaaki Akaike
openalex   +1 more source

Development of a Homogeneous High-Throughput Screening Assay for Biological Inhibitors of Human Rhinovirus Infection [PDF]

, 2012
Philip M. Newton, Desmond J. O'Shea, Edward Wells, Kerry Moakes, Rebecca Dunmore, Robin Butler, Trevor Wilkinson, Alison Ward, Nigel Casson, Martin Strain, Katherine A. Vousden, David C. Lowe, Debbie V. Pattison, Alan Carruthers, Matthew A. Sleeman, Tristan J. Vaughan, Paula Harrison   +16 more
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source