Results 31 to 40 of about 2,148,890 (355)

Immunosensors for Assay of Toxic Biological Warfare Agents

Biosensors, 2023
An immunosensor for the assay of toxic biological warfare agents is a biosensor suitable for detecting hazardous substances such as aflatoxin, botulinum toxin, ricin, Shiga toxin, and others.
Miroslav Pohanka
doaj   +1 more source

Iterative focused screening with biological fingerprints identifies selective Asc-1 inhibitors distinct from traditional high throughput screening [PDF]

, 2017
N-methyl-d-aspartate receptors (NMDARs) mediate glutamatergic signaling that is critical to cognitive processes in the central nervous system, and NMDAR hypofunction is thought to contribute to cognitive impairment observed in both schizophrenia and ...
Amoss, Adam, Cassaday, Jason A., Cooke, Andrew J., Culberson, J. Chris, Finley, Michael, Hermes, Jeffrey D., Hurzy, Danielle, Johnson, Eric N., Kutchukian, Peter S., Magliaro, Brian C., O’Donnell, Gregory, Parmentier-Batteur, Sophie, Pascarella, Danette, Schlegel, Kelly-Ann Sondra, Squadroni, Brian, Thomson, Fiona, Uebele, Victor N., Warren, Lee, Zuck, Paul   +18 more
core   +2 more sources

Verapamil protects against hyperuricemia nephropathy through modulating TXNIP/NLRP3 inflammasome signaling pathway

陆军军医大学学报
Objective‍　‍To investigate the protective effect of verapamil on hyperuricemia nephropathy (HN) in mice through modulating TXNIP/NLRP3 inflammasome signaling pathway.
WANG Ting, WANG Ting, LI Li , ZHU Xin
doaj   +1 more source

Computation of Biological Assays [PDF]

Nature, 1946
IN microbiological assays of essential amino-acids, and of members of the vitamin B2 complex other than riboflavin and nicotinic acid, it is usually found that when the mean responses are plotted against either the dose or the logarithm of the dose, a non linear relationship is obtained.
openaire   +2 more sources

The lncRNA landscape of breast cancer reveals a role for DSCAM-AS1 in breast cancer progression. [PDF]

, 2016
Molecular classification of cancers into subtypes has resulted in an advance in our understanding of tumour biology and treatment response across multiple tumour types. However, to date, cancer profiling has largely focused on protein-coding genes, which
Backofen, Rolf, Cao, Xuhong, Chinnaiyan, Arul M, Collins, Colin, Feng, Felix Y, Gawronski, Alexander, Han, Sumin, Hayes, Daniel F, Hosono, Yasuyuki, Iyer, Matthew K, Kregel, Steven, Ma, Teng, Malik, Rohit, Niknafs, Yashar S, Pierce, Lori J, Pitchiaya, Sethuramasundaram, Poliakov, Anton, Prensner, John R, Rae, James M, Sahinalp, Cenk S, Siebenaler, Ronald F, Singhal, Udit, Speers, Corey, Uhl, Michael, Wilder-Romans, Kari, Xiao, Lanbo, Zhang, Chao, Zhao, Shuang G   +27 more
core   +1 more source

Hematite Nanoparticles Synthesized by Green Route: Characterization, Anticancer and Antioxidant Activities

Inorganics
Recently, attention has shifted towards the green synthesis of nanoparticles using plant extracts rich in phytochemicals like phenols and flavonoids, offering an alternative method that avoids harmful chemicals and enables large-scale, low-cost ...
Safa Ezzine, Hela Ferjani, Oluwasayo E. Ogunjinmi, Damian C. Onwudiwe   +3 more
doaj   +1 more source

Highly Mutable Linker Regions Regulate HIV-1 Rev Function and Stability. [PDF]

, 2019
HIV-1 Rev is an essential viral regulatory protein that facilitates the nuclear export of intron-containing viral mRNAs. It is organized into structured, functionally well-characterized motifs joined by less understood linker regions.
Fernandes, Jason D, Frankel, Alan D, Jayaraman, Bhargavi, Smith, Cynthia, Yang, Shumin   +4 more
core   +3 more sources

Genomic stability in response to high versus low linear energy transfer radiation in Arabidopsis thaliana. [PDF]

, 2014
Low linear energy transfer (LET) gamma rays and high LET HZE (high atomic weight, high energy) particles act as powerful mutagens in both plants and animals.
Britt, Anne B, Conklin, Phillip A, Friesner, Joanna D, Huefner, Neil D, Yoshiyama, Kaoru   +4 more
core   +1 more source

A Novel Serum-Based Bioassay for Quantification of Cancer-Associated Transformation Activity: A Case–Control and Animal Study

Diagnostics
Background/Objectives: The detection of ovarian cancer remains challenging due to the lack of reliable serum biomarkers that reflect malignant transformation rather than mere tumor presence.
Aye Aye Khine, Hsuan-Shun Huang, Pao-Chu Chen, Chun-Shuo Hsu, Ying-Hsi Chen, Sung-Chao Chu, Tang-Yuan Chu   +6 more
doaj   +1 more source

A high throughput molecular force assay for protein-DNA interactions. [PDF]

, 2011
An accurate and genome-wide characterization of protein–DNA interactions such as transcription factor binding is of utmost importance for modern biology. Powerful screening methods emerged.
Albrecht, Albrecht, Bartels, Berger, Bizzarri, Blank, Bulyk, Bustamante, Bustamante, Cao, Dominik Ho, Dose, Evans, Gittes, Harbison, Hermann E. Gaub, Ho, Ho, Iyer, Jeltsch, Jen-Jacobson, Koch, Koch, Kuhner, Lee, Lesser, Maerkl, Merkel, Morfill, Moy, Mukherjee, Philip M. D. Severin, Pincet, Ren, Rief, Segal, Sidorova, Sidorova, Strunz, Uhrig, Viani, Wiegand, Wu   +42 more
core   +1 more source