Results 91 to 100 of about 1,829,061 (296)

Using CRISPR/Cas9 for Large Fragment Deletions in Saccharomyces cerevisiae

Bio-Protocol, 2017
CRISPR/Cas9 (Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-associated protein 9) systems have emerged as a powerful tool for genome editing in many organisms.
Huanhuan Hao, Jing Huang, Tongtong Liu, Hui Tang, Liping zhang   +4 more
doaj   +1 more source

Emergence of diversity in a model ecosystem

, 2012
The biological requirements for an ecosystem to develop and maintain species diversity are in general unknown. Here we consider a model ecosystem of sessile and mutually excluding organisms competing for space [Mathiesen et al. Phys. Rev. Lett.
D. Mollison, G. Gause, Joachim Mathiesen, Kim Sneppen, M. Eigen, Namiko Mitarai, R. M. May, V. Volterra   +7 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

GMOD for Evolutionary Biology [PDF]

, 2010
The Generic Model Organism Database (GMOD, "http://gmod.org":http://gmod.org) project provides interoperable, open source software tools for managing, visualizing and annotating biological data.
Dave Clements, Robert Buels
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Comparing farm and village-level determinants of millet diversity in marginal environments of India: the context of seed systems [PDF]

"The purpose of the research paper is to characterize biological diversity related to millets in the semi-arid regions of India at various spatial scales of analysis (e.g., farm household versus community levels) and place that evidence in a broader seed
Glewwe, Paul, Nagarajan, Latha, Smale, Melinda   +2 more
core  

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

In vitro effect-based monitoring of water, sediment and soil from a floodplain restoration site in Central Europe

Environmental Sciences Europe
Background Floodplains are biodiversity hotspots and provide numerous ecosystem services. In recent decades, however, 70–90% of Europe’s floodplains have been structurally degraded.
Nina Kuschik-Maczollek, Malte Glock, Markus Schmitz, Henner Hollert, Martin Krauss, Aleksandra Piotrowska, Werner Brack, Jörg Oehlmann   +7 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

The Impact of Seasonal Changes in Plant Tissue on Rhizogenesis of Stem Cuttings of Once Blooming Roses

Notulae Botanicae Horti Agrobotanici Cluj-Napoca, 2016
The majority of old and long-to-root roses are enough frost resistant to grow on their own roots in moderate and cool climates. The more often used method of rose propagation are single node stem cuttings derived from blooming shoots.
Marta Joanna MONDER, Andrzej PACHOLCZAK, Konrad WOLIŃSKI, Maciej NIEDZIELSKI   +3 more
doaj   +1 more source