Results 71 to 80 of about 594,729 (258)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Regional trade of medicinal plants has facilitated the retention of traditional knowledge: case study in Gilgit-Baltistan Pakistan

open access: yesJournal of Ethnobiology and Ethnomedicine, 2019
Background The ethnic groups in Gilgit-Baltistan have been utilizing local resources in their centuries-old traditional healing system. Most tribes within these ethnic groups still rely on traditional healing systems.
Muhammad Asad Salim   +9 more
doaj   +1 more source

Enhancing chemical and biological diversity by co-cultivation. [PDF]

open access: yesFront Microbiol, 2023
Selegato DM, Castro-Gamboa I.
europepmc   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Malaria Risk Drivers in the Brazilian Amazon: Land Use-Land Cover Interactions and Biological Diversity. [PDF]

open access: yesInt J Environ Res Public Health, 2023
Gonzalez Daza W   +3 more
europepmc   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Adelphomyia crane flies (Diptera, Limoniidae) of Korea with identification key for all Palaearctic species [PDF]

open access: yesZooKeys
Limnophilinae crane flies belonging to the genus Adelphomyia Bergroth, 1891 of the Korean Peninsula were studied starting from 1937, but only one species A. macrotrichiata (Alexander, 1923) has been recorded from North Korea so far. The genus was unknown
Sigitas Podenas   +2 more
doaj   +3 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Temporal genomics in Hawaiian crickets reveals compensatory intragenomic coadaptation during adaptive evolution

open access: yesNature Communications
Theory predicts that compensatory genetic changes reduce negative indirect effects of selected variants during adaptive evolution, but evidence is scarce.
Xiao Zhang   +10 more
doaj   +1 more source

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