Results 151 to 160 of about 2,108,914 (342)
Utilization of algal beach wracks as a supplementary substrate for enhancing mushroom production
Frontiers in Marine ScienceDespite ecological protections, the Mar Menor lagoon in Spain continues to experience eutrophication, leading to uncontrolled proliferation of algae such as Caulerpa prolifera.
Rebeca Lavega +6 more
doaj +1 more source
Analysis of Biological Selections for High-Efficiency Gene Targeting
, 1995 Keith D. Hanson, John M. Sedivy
openalex +2 more sources
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Biological activity of binary triazole preparations on soft spring wheat
Siberian Journal of Life Sciences and AgricultureBackground. Integrated plant protection against diseases, pests and weeds is the most important element of agricultural technology. The use of fungicides is important not only to increase plant yields, but also to obtain high-quality crops. Most chemical
Natalia G. Vlasenko +4 more
doaj +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Ciência Rural, 2010 A escolha da camada de cobertura é uma das mais importantes etapas do cultivo de Agaricus brasiliensis. Apesar dessa importância, poucos estudos relatam o uso de diferentes tratamentos térmicos para o controle da microbiota em camadas de cobertura ...
Nelson Barros Colauto +3 more
doaj