Results 201 to 210 of about 2,108,914 (342)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

A Plug-in system for reprogramming the editing patterns of base editors. [PDF]

Nat Commun
Zhong C, Yu L, Zhao T, Shen X, Li Z, Zhu W, Hu Z, Tian R, Han Z, He D.   +9 more
europepmc   +1 more source

Hydrogen sulfide biological removal efficiency by vermicompost horizontal biofilter

, 2020
Weiping Tian, Xuemin Chen, Peng Zhou, Xiaoyong Fu   +3 more
openalex   +1 more source

96. Does a structured approach in the form of a rheumatology virtual biologics clinic improve patient safety and efficiency? [PDF]

, 2018
Muhamad Jasim, G. Radford Smith, Sharon Petford, Lisa Jones, Holly John   +4 more
openalex   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Bio-inspired unified model for representing geometric relations in robotic perception. [PDF]

Sci Rep
Yi Y, Zhuo W, Huifeng W, Danfeng S, Simon R.   +4 more
europepmc   +1 more source

Effects of Different Substrates on Lignocellulosic Enzyme Expression, Enzyme Activity, Substrate Utilization and Biological Efficiency of Pleurotus Eryngii

, 2016
Chunliang Xie, Yan Li, Wenbing Gong, Zuohua Zhu, Senwei Tan, Du Chen, Zhenxiu Hu, Yuande Peng   +7 more
openalex   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Cross-scale design of abiotic-biotic interfaces for semi-artificial photosynthesis. [PDF]

Chem Sci
Wang H, Li J, Feng Y, He D, Fan X, Wang B, Cai Z, Zeng C, Xiao K.   +8 more
europepmc   +1 more source

Efficiency Increase of Biological Methanation based Power-to-Methane Technology Using Waste Heat Recovery with Organic Rankine Cycle

, 2022
Axel Groniewsky, Réka Kustán, Attila R. Imre   +2 more
openalex   +2 more sources