Results 191 to 200 of about 970,591 (266)

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Microbial co-inoculation and extracellular vesicles: new frontiers for soybean productivity. [PDF]

Antonie Van Leeuwenhoek
Fulaneti FS, Brasil-Neto ES, Rumpel VS, de Paula Ribeiro L, Brum LN, Cipriani LP, Martin TN.   +6 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Dietary biological silage from tambaqui by products affect performance, physiology, and egg quality of young and old laying hens. [PDF]

Trop Anim Health Prod
Guimarães CC, Rufino JPF, Barai AA, de Almeida Santos AN, da Silva Gomes MF, Nóbrega TC, Ribeiro MWS, da Silva Castro PD, Mendes JM, de Lima Chaves FA, da Silva Junior JL, de Freitas Mendonça MA, de Jesus Beltrão Machado N, de Oliveira AT.   +13 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Emerging paradigms in nanostructured targeted drug delivery systems. [PDF]

Discov Nano
Hasnain AN, Telange DR.
europepmc   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Different Strains of Microalgae in a Microbial Consortium Remove Antibiotics from Urban Wastewater in Batch and Continuous Treatment Systems. [PDF]

ACS Omega
Vargas SR, de Lima Santos J, Ferraz Ribeiro PH, Alcântara IM, Carneiro RB, Zaiat M.   +5 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Oxidative Stress, Antioxidant Defense, and Sleep-Wake Regulation in Psychiatric Disorders. [PDF]

Antioxidants (Basel)
Ohayon MM.
europepmc   +1 more source