Results 201 to 210 of about 10,327,060 (336)

Preparation, molecular docking, and biological evaluation of radioiodinated cefaclor for inflammation detection. [PDF]

BMC Pharmacol Toxicol
Hussien H, El Refaye MS, Aglan H, Challan SB, Khater SI.   +4 more
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Exosomes as Emerging Nanocarriers for Targeted Cancer Therapy. [PDF]

Int J Nanomedicine
Du Y, Liu D, Liu J, Yu J, Hao Z, Zhang M, Li J, Peng X.   +7 more
europepmc   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

The robust, high-throughput, and temporally regulated roxCre and loxCre reporting systems for genetic modifications in vivo. [PDF]

Elife
Shi M, Li J, Liu X, Liu K, He L, Pu W, Weng W, Zhang S, Zhao H, Lui K, Zhou B.   +10 more
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Deep-Sea Biomimetic Manta Ray Robots: A Comprehensive Review Based on Operational Depth Spectrum, Structures, Energy Optimization, and Control Systems. [PDF]

Biomimetics (Basel)
Ye L, Liu H, Ding Q, Hu Z, Li W, Cui W, Fan D.   +6 more
europepmc   +1 more source

Yield Performance and Biological Efficiency of Empty Fruit Bunch (EFB) and Palm Pressed Fibre (PPF) as Substrates for the Cultivation of Pleurotus Ostreatus

, 2013
N. Ali, Amal Nafissa Mohd. Tabi, F. A. Zakil, Wan Nur Fauzan Mohd. Fauzai, Onn Hassan   +4 more
semanticscholar   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Rationally and in silico guided APOBEC3F-directed CBE for enhanced PDAC genetic therapy. [PDF]

Commun Biol
Fang Q, Zhang J, Wang K, Wang Z, Lv Z, Zhang X, Bi C, Zhang X, Yu J, Feng Y, Zhou T, Hao J, Yang C.   +12 more
europepmc   +1 more source