Results 181 to 190 of about 1,034,919 (313)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Investigation on the Efficiency of Verticillium-Psalliotae Treschow in Biological Control of Early Blight of Tomatoes

open access: yes, 1994
3rd Turkish National Congress of Biological Control -- JAN 25-28, 1994 -- IZMIR, TURKEY[Abstract not ...
Yiğit, F., Turhan, G.
core  

The relative biological efficiencies of the vitamin A and carotene of butter [PDF]

open access: yesBiochemical Journal, 1934
Roland Gordon Booth   +2 more
openaire   +2 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Stochastic Frontier Analysis of Biological Agents (Microbial Inoculants) Input Usage in Apple Production

open access: yes
In this paper, we analyze the impact of the Microbial Inoculants (MI) Technology on apple yields and pesticide application using 2007 farm data. The results show that pesticide usage is not reduced by MI applications.
Kloepper, Joseph   +2 more
core  

THE BIOLOGICAL EFFICIENCY OF POTATO NITROGEN

open access: yesJournal of Biological Chemistry, 1917
Mary S. Rose, Lenna F. Cooper
openaire   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

Analysis of energy efficiency in broiler farms in Bursa, Turkey

open access: yes, 2014
Energy use in the broiler sector has grown with increasing population and standard of living. The aim of this study was to determine energy use, energy efficiency and energy consumption for broiler farms in the Bursa region of western Turkey.
Kılıç, I.   +2 more
core  

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