Results 91 to 100 of about 1,840,126 (315)

Single cis‐elements in brassinosteroid‐induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA‐binding domain

FEBS Letters, EarlyView.
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki, Masae Ohtsuka, Takeshi Nakano, Masaru Tanokura, Takuya Miyakawa   +4 more
wiley   +1 more source

The Effect of Plant Supplements on the Development of Artificially Weaken Bee Families

Scientific Papers Animal Science and Biotechnologies, 2023
In this study, infusions from nettle, thyme and Echinacea, fresh juice of onion and garlic, and Protofil (alcoholic extract of different plants enriched with vitamins and mineral elements), were used in supplementary feeding of artificially weaken bee ...
Liviu Al. Mărghitaș, Otilia Bobiș, Melinda Tofalvi   +2 more
doaj  

Cultural and Biological Evolution [PDF]

, 2021
AbstractAlthough there is no necessary relation between “big data” and “monism”—the program of reducing cultural and mental processes to computational and biological principles—both these programs reject a dualism between res extensa and res cogitans. Opposing this philosophy of science, I have argued in the above chapter that a second contingency of ...
openaire   +2 more sources

Mass Extinctions vs. Uniformitarianism in Biological Evolution

, 1995
It is usually believed that Darwin's theory leads to a smooth gradual evolution, so that mass extinctions must be caused by external shocks. However, it has recently been argued that mass extinctions arise from the intrinsic dynamics of Darwinian ...
Bak, Per, Paczuski, Maya
core   +3 more sources

Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment

FEBS Letters, EarlyView.
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke, Nils Alexander Lakomek, Georg Groth   +2 more
wiley   +1 more source

Axiological and epistemological contributions to teaching the theory of evolution Darwin [PDF]

Investigações em Ensino de Ciências, 2011
From the essential role of theme “biological evolution” in scientific formation of students and the diversity of issues identified in the literature for teaching of the same, we developed a qualitative study through contributions of Didactics of Science ...
Lucken Bueno Lucas, Irinéa de Lourdes Batista   +1 more
doaj  

The C-value enigma and timing of the Cambrian explosion

, 2008
The Cambrian explosion is a grand challenge to science today and involves multidisciplinary study. This event is generally believed as a result of genetic innovations, environmental factors and ecological interactions, even though there are many ...
Adami, Bousso, Bromham, Carter, Conway Morris, Davidson, Davidson, Dirson Jian Li, Gregory, Hedges, Kauffman, Knoll, Knoll, Kumar, Larroux, Li, Li, Lynch, Mattick, Mattick, Mojzsis, Peltier, Peterson, Sharov, Shengli Zhang, Shmulevich, Shu, Trevors, Valentine, Wada   +29 more
core   +1 more source

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

FEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer, Philip Hinchliffe, Marko Hanževački, Christopher R. Bethel, Catherine L. Tooke, Marc W. Van der Kamp, Krisztina M. Papp‐Wallace, Robert A. Bonomo, Stuart Shapiro, Adrian J. Mulholland, James Spencer   +10 more
wiley   +1 more source

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

FEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican, Yara Nabawi, William Hongyu Zhang, Dunja Petrovic, Markus Wehrmann, Sara Muñoz‐García, Seda Koyuncu, David Vilchez   +7 more
wiley   +1 more source

The Basics of Evolution Strategies: The Implementation of the Biomimetic Optimization Method in Educational Modules

Biomimetics
With a focus on education and teaching, we provide general background information on bioinspired optimization methods by comparing the concept of optimization and the search for an optimum in engineering and biology.
Olga Speck, Thomas Speck, Sabine Baur, Michael Herdy   +3 more
doaj   +1 more source