Results 91 to 100 of about 7,103,771 (354)
Reactive Oxygen Species Signaling and Oxidative Stress: Transcriptional Regulation and Evolution
AntioxidantsSince the evolution of the aerobic metabolism, reactive oxygen species (ROS) have represented significant challenges to diverse life forms. In recent decades, increasing knowledge has revealed a dual role for ROS in cell physiology, showing they serve as
Yuhang Hong +3 more
semanticscholar +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Degeneracy: a design principle for achieving robustness and evolvability
, 2009 Robustness, the insensitivity of some of a biological system's functionalities to a set of distinct conditions, is intimately linked to fitness. Recent studies suggest that it may also play a vital role in enabling the evolution of species.
Bender, Axel, Whitacre, James M
core +1 more source
P658 Evolution of disease phenotype, time to biological therapy and medium-, long-term colectomy rates in Ulcerative Colitis patients in Western Hungary – a population-based study between 2007–2018, data from the Veszprem county cohort [PDF]
, 2022 Lóránt Gönczi +7 more
openalex +1 more source
Rapid evolution of dispersal ability makes biological invasions faster and more variable
Nature Communications, 2017 Genetic variation in dispersal ability may result in the spatial sorting of alleles during range expansion. Recent theory suggests that spatial sorting can favour the rapid evolution of life history traits at expanding fronts, and therefore modify the ...
Brad M. Ochocki, T. Miller
semanticscholar +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Race in the Life Sciences: An Empirical Assessment, 1950-2000 [PDF]
, 2015 The mainstream narrative regarding the evolution of race as an idea in the scientific community is that biological understandings of race dominated throughout the nineteenth and twentieth centuries up until World War II, after which a social ...
Darling, Katherine +3 more
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BIOLOGY AND THE SOCIAL SCIENCES
Zygon, 1990 . The sciences may be conceptualized as a hierarchy ranked by level of organization (e.g., many‐body physics ranks above particle physics). Each science serves as an antidiscipline for the science above it; that is, between each pair, tense but creative
doaj +2 more sources
Scientific Reports, 2017 Gene Ontology (GO) enrichment analysis is ubiquitously used for interpreting high throughput molecular data and generating hypotheses about underlying biological phenomena of experiments.
Aurelie Tomczak +11 more
semanticscholar +1 more source
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source