Results 61 to 70 of about 1,840,126 (315)

Mechanisms and kinetic assays of aminoacyl‐tRNA synthetases

FEBS Letters, EarlyView.
Accurate protein synthesis is crucial for life. The key players are aminoacyl‐tRNA synthetases (AARSs), which read the genetic code by pairing cognate amino acids and tRNAs. AARSs establish high amino acid selectivity by employing physicochemical limits in molecular recognition.
Igor Zivkovic, Morana Dulic, Ita Gruic‐Sovulj   +2 more
wiley   +1 more source

Different effects of accelerated development and enhanced growth on oxidative stress and telomere shortening in amphibian larvae

Scientific Reports, 2017
Organisms react to environmental changes through plastic responses that often involve physiological alterations with the potential to modify life-history traits and fitness. Environmentally induced shifts in growth and development in species with complex
Pablo Burraco, Carmen Díaz-Paniagua, Ivan Gomez-Mestre   +2 more
doaj   +1 more source

Origin of Life: The Point of No Return

Life, 2020
Origin of life research is one of the greatest scientific frontiers of mankind. Many hypotheses have been proposed to explain how life began. Although different hypotheses emphasize different initial phenomena, all of them agree around one important ...
Dimiter Kunnev
doaj   +1 more source

Monte Carlo Simulation of Age-Dependent Host-Parasite Relations

, 2007
The death of a biological population is an extreme event which we investigate here for a host-parasitoid system. Our simulations using the Penna ageing model show how biological evolution can ``teach'' the parasitoids to avoid extinction by waiting for ...
Ana Proykova, Dietrich Stauffer, Karl-Heinz Lampe, Lampe, Malarz, Moss de Oliveira, Pal, Stauffer   +7 more
core   +2 more sources

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Digital Lovers and Jealousy: Anticipated Emotional Responses to Emotionally and Physically Sophisticated Sexual Technologies

Human Behavior and Emerging Technologies
Technologies that stimulate human social and sexual impulses could affect users and societies. Here, we report on two experiments designed to test participant responses to (1) “virtual friend” chatbots that vary in capacity to engage users socially and ...
Ashton Prochazka, Robert C. Brooks
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Chemical and biological evolution in space

Advances in Space Research, 1984
Astronomical infrared spectra are used to confirm the existence of complex organic molecules produced by ultraviolet photoprocessing of interstellar grain mantles. This material is shown to be the major component of the interstellar grains between the sun and the galactic center and, by inference, constitutes more than 10 million solar masses--or close
Mayo Greenberg, J., Weber, P., Schutte, W.A.   +2 more
openaire   +4 more sources

Mapping posthuman discourse and the evolution of living information [PDF]

, 2006
The discourse that surrounds and constitutes the post-human emerged as a response to earlier claims of an essential or universal human or human nature.
Swift, Adam Glen
core   +1 more source

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

FEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li, Gerard van der Zon, Peter ten Dijke, Tong Shen   +3 more
wiley   +1 more source