Results 111 to 120 of about 5,611,755 (345)

Miniaturised Extraction Techniques in Personalised Medicine: Analytical Opportunities and Translational Perspectives

open access: yesMolecules
Miniaturised sampling and extraction are redefining therapeutic drug monitoring (TDM) by enabling low-volume sampling, simplifying collection, and improving patient acceptability, while also promoting decentralised workflows and more sustainable ...
Luana M. Rosendo   +3 more
doaj   +1 more source

Surface coating affects behavior of metallic nanoparticles in a biological environment

open access: yesBeilstein Journal of Nanotechnology, 2016
Silver (AgNPs) and maghemite, i.e., superparamagnetic iron oxide nanoparticles (SPIONs) are promising candidates for new medical applications, which implies the need for strict information regarding their physicochemical characteristics and behavior in a
Darija Domazet Jurašin   +8 more
doaj   +1 more source

A Simple and High-Throughput Analysis of Amatoxins and Phallotoxins in Human Plasma, Serum and Urine Using UPLC-MS/MS Combined with PRiME HLB μElution Platform

open access: yesToxins, 2016
Amatoxins and phallotoxins are toxic cyclopeptides found in the genus Amanita and are among the predominant causes of fatal food poisoning in China.
Shuo Zhang   +7 more
doaj   +1 more source

Nano- and microparticles at fluid and biological interfaces

open access: yesJournal of Physics: Condensed Matter, 2017
Systems with interfaces are abundant in both technological applications and biology. While a fluid interface separates two fluids, membranes separate the inside of vesicles from the outside, the interior of biological cells from the environment, and compartmentalize cells into organelles.
Dasgupta, S, Auth, T, Gompper, G
openaire   +3 more sources

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Analysis of Theobromine and Related Compounds by Reversed Phase High-Performance Liquid Chromatography with Ultraviolet Detection: An Update (1992–2011)

open access: yesFood Technology and Biotechnology, 2011
Theobromine and its related compounds, such as caffeine and theophylline, are secondary metabolites that belong to the alkaloids and have economic and cultural importance.
Sandra Aparecida de Assis   +2 more
doaj  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Complex fluids in biological systems: experiment, theory, and computation

open access: yes, 2015
This book serves as an introduction to the continuum mechanics and mathematical modeling of complex fluids in living systems. The form and function of living systems are intimately tied to the nature of surrounding fluid environments, which commonly ...
Spagnolie, Saverio
core   +1 more source

Some more about dogs: Proteomics of neglected biological fluids

open access: yes, 2020
We report in this manuscript what is known about the protein makeup of a selection of biological fluids in the domestic dog. The samples we review – amniotic and allantoic fluid, seminal fluid, saliva, bile, synovial fluid, tears – are still very poorly ...
Gianazza E   +5 more
core   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

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