Results 121 to 130 of about 5,611,755 (345)
Approaches Toward Allowing Electroanalytical Devices to be Used in Biological Fluids
, 2014 Biofouling on surfaces can deleteriously affect the function of electrochemical sensor used in a biological fluid. The demand is thus to develop a sensor operatable in complex matrices.
A. Barfidokht, J. Gooding
semanticscholar +1 more source
Analysis of some B-adrenergic agonists in biological matrices after evaluation of various extraction methodologies and determination procedures [PDF]
, 1994 Biological sample clean-up procedures were evaluated for the extraction of a range of /3-agonists. Once extracted the compounds were determined by immunoassay, electrochemical techniques and supercritical fluid chromatography (SFC).
Boyd, Damien Thomas
core
Decomposition Kinetics of Cisplatin in Human Biological Fluids
, 1996 Cisplatin is metabolized to high- and low-molecular mass complexes by exchanging of one or both chloride ligands with nucleophilic species. The decomposition of cisplatin and the formation of its metabolites in human biological fluids was investigated in-
N Nagai, M Kinoshita, H Ogata, R Okuda
core +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
, 1986 Six cysteine proteinase inhibitors were isolated from human urine by affinity chromatography on insolubilized carboxymethylpapain followed by ion-exchange chromatography and immunosorption.
Salvesen, Guy +4 more
core
Using bioinformatic resources in the proteomic analysis of biological fluids
, 2007 On-line databases targeted towards protein contents in biological fluids are scarce. Consequently, the investigation of proteins identified in a biological fluid most importantly depends on crosschecking information gathered from less specific resources.
Lisacek, Frédérique +4 more
core +1 more source
Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis
Molecular Oncology, EarlyView.LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini +1 more
wiley +1 more source
S100B protein in biological fluids: a tool for perinatal medicine
, 2002 The diagnosis of perinatal insults currently relies on adequate documentation of general medical and obstetric factors and on radiologic and laboratory assessments.
Michetti, Fabrizio, Gazzolo, Diego
core
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source